Enhanced cingulate activity while anticipating pain – evidence for altered ‘top down’ processing of pain in PD
Objective: To investigate the hypothesis that altered ‘top down’ processing contributes to the development of pain in Parkinson’s disease (PD). Background: Altered ‘top down’ processing…Investigation of the incidences of non-motor symptoms in first-degree relatives and the spouses of patients with Parkinson’s disease
Objective: The first-degree relatives of PD patients (such as siblings) and the spouses living together for many years do not have classic motor symptoms. However,…The comparative clinical analysis of sleep patterns in patients with Amyotrophic Lateral Sclerosis and Parkinson’s disease
Objective: We seek to investigate the nighttime sleep pattern of neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS) and primary Parkinson's disease (PD). Background: Sleep disorders…Communication and Swallowing Disorders in People with Parkinson’s disease: A National Survey on Everyday Impacts and Service Access
Objective: To investigate people with Parkinson’s disease’s (PwPD) 1) communication and swallowing difficulties; 2) participation and psychosocial impacts of these difficulties 3) experience with and…Examination of paravertebral muscular force in camptocormia
Objective: To measure the force of paravertebral muscle of PD patients with camptocormia compared to PD patients without camptocormia and healthy controls to assess the…Presence of Lewy dots in the brain of patients with Creutzfeldt-Jakob disease
Objective: We have investigated whether alpha-synuclein deposits exists in the brain of patients with Creutzfelt-Jakob disease Background: Creutzfeldt-Jakob’s disease (CJD) is a prion neurodegenerative disorder…Cell and animal models lacking RAB39B show biochemical and behavioural phenotypes that model aspects of Parkinson’s disease
Objective: To determine the pathogenic mechanisms underlying RAB39B-mediated Parkinson’s disease (PD). Background: PD is a neurodegenerative disorder characterized by loss of dopaminergic neurons in the…Determination of falling direction in Parkinson’s disease patients using a wearable sensor
Objective: The aim of this study is to objectively detect falls and their direction in Parkinson’s disease (PD) patients during everyday activities. Background: Falling is…Neuroprotection effects of probiotics strains on a chronic MPTP-induced mouse model of Parkinson’s disease
Objective: To explore the effects of probiotics strains on the neuroinflammation and degeneration of dopaminergic neurons in chronic Parkinson’s disease (PD) mice model. Background: Microglia-mediated…Speech intelligibility and comprehensibility in Slovak patients with Parkinson’s disease
Objective: The aim of our study was to evaluate intelligibility and comprehensibility (intelligibility in context) and its relationship with MDS-UPDRS (sub)scores in Slovak population of…
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