Clinical correlates of stuttering in advanced Parkinson’s disease
Objective: We investigated clinical characteristics of a large number of advanced Parkinson’s disease (PD) patients to reveal risk factors for the development of stuttering and…Modulation of CaMKIIa-NR2B interaction in levodopa-induced dyskinesia in 6-OHDA- lesioned Parkinson’s rats
Objective: In the present study, therefore, we examined the relationship between CaMKII and NR2B in levodopa-induced dyskinesia rats. Background: Long-term treatment with L-dopa leads to…Impaired performance on measures of goal-directed behavior are associated with greater caregiver burden in Parkinson’s disease
Objective: To assess the utility of the Philadelphia Apathy Computerized Task (PACT) in measuring goal-directed behavior in Parkinson’s disease (PD). Background: Impairment in goal-directed behavior…Patient Experience of Parkinson’s Disease Psychosis Management
Objective: To understand the experience and management of Parkinson’s disease psychosis (PDP). Background: PDP is a troubling non-motor symptom of Parkinson’s disease. Clinical approaches to…Rasch analysis of the Hospital Anxiety and Depression Scale among patients with early-stage Parkinson’s disease
Objective: We aim to assess the psychometric properties of the Korean version of Hospital Anxiety and Depression Scale (HADS) in a sample of early-stage Parkinson's…Effect of PD medication on disease progression as measured by rate of change in MDS_UPDRS and DaT SBR in PPMI study
Objective: In clinical trials for new PD therapies, it is common for patients to start to take approved symptomatic PD medications during the study. The…Efficacy of zonisamide on motor symptoms in dementia with Lewy bodies: A post-hoc analysis of a phase 3 study
Objective: To characterize the efficacy of zonisamide in improving motor symptoms, we performed a post-hoc analysis using data from a phase 3 study that evaluated…Proof-of-Principle Quantitative EEG Study of CX-8998, an Oral, Potent and Selective T-Type Calcium antagonist in development for symptomatic treatment of Essential Tremor and Parkinson’s disease Tremor
Objective: To study the pharmacodynamics (PD) of CX-8998, using pharmaco-electroencephalography (phEEG) and define plasma concentrations of CX-8998 which are pharmacologically active on objective CNS parameters.…Motor and non-motor correlates of APOE-ε4 mediated cerebrospinal fluid concentrations of biomarkers of amyloidogenesis and neurodegeneration in dementia with Lewy bodies compared with Alzheimer’s dementia and healthy controls
Objective: To study associations of cerebrospinal fluid biomarkers of amyloidogenesis and neurodegeneration with motor and non-motor aspects of daily experiences in dementia with Lewy bodies…Molecular immunological action and epigenetic modification of the human papillomavirus vaccination and associated neuropsychiatric side effects
Objective: To investigate the clinical manifestations of neuropsychiatric side effects after the Human papillomavirus (HPV) vaccine, and to investigate the immunological actions and epigenetic modification.…
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