SYN120 (a Dual 5-HT6/5-HT2A Antagonist) Study to Evaluate Safety, Tolerability and Efficacy in Parkinson’s Disease Dementia (SYNAPSE): Phase 2a Study Results
Objective: To evaluate the safety and preliminary efficacy of SYN120 in patients with Parkinson's disease dementia (PDD). Background: SYN120 is an antagonist of serotonin receptors…Delayed-onset Edema Surrounding Deep Brain Stimulation Leads: Insights From A Case Series and Literature Review
Objective: We report a case that showed Postoperative cerebral edema around a deep brain stimulation (DBS) electrode and review the literature to explore its possible causes. Background: Deep brain…A Study to Evaluate the Efficacy of PRX002/RG7935 in Participants With Early Parkinson’s Disease (PASADENA) – Study Design
Objective: To evaluate the efficacy of the anti-alpha-synuclein monoclonal antibody PRX002/RG7935 in a proof-of-concept Phase 2 study in patients with early Parkinson’s disease (PD). Background:…Study On Patient- And Caregiver-Reported Symptoms And Outcomes With Levodopa-Carbidopa Intestinal Gel For The Treatment Of Advanced Parkinson’s Disease. ADEQUA Study
Objective: The primary objective of the present study was to assess the effect of levodopa-carbidopa intestinal gel (LCIG) on the QoL of patients with advanced…A Computer-Aided Prescription Model for Parkinson’s Disease could predict the suitable drugs for Parkinson’s disease (PD) patients
Objective: Using machine learning techniques to automatically recommend suitable drugs for Parkinson’s Disease (PD) patients, thereby providing computer-aided prescriptions. Background: PD is the second most…Effect of Ba Duan Jin Exercise on Non-Motor Symptoms, Motor Symptoms, Gait and Balance in Patients with Mild to Moderate Parkinson’s Disease
Objective: There are many traditional exercises in China such as Taijiquan, Wuqianxi and Ba Duanjin. Studies have shown that Taijiquan can help to improve the…Management of chronic polyneuropathy associated with levodopa-carbidopa intestinal gel infusion in Parkinson’s disease: Review of the strategies and perspectives
Objective: (1) To make an inventory of the current strategies used to treat or prevent the occurrence of chronic polyneuropathy (CPN) in patients with Parkinson’s…Evaluation clinical-biochemical features of Parkinson’s disease
Objective: To study the features of the cytokine status under different forms and variants of PD course. Background: Parkinson’s disease is clinically heterogeneous; the etiology…Correlation between severity of disease, spatio-temporal variables, and kinematic variables during forward and backward walking
Objective: The purpose of this study was to analyze the correlation between disease severity and variable by using spatio-temporal and kinematic variables during forward and…Perceived Psychosocial Impacts of a Therapeutic Yoga Intervention for Individuals with Parkinson’s Disease (PD)
Objective: This qualitative study sought to understand the psychosocial impacts of a therapeutic yoga intervention for individuals with PD originally designed to improve balance and…
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