Turning during gait is associated with gray matter density of the nucleus basalis of Meynert in Parkinson’s disease
Objective: To examine whether turning during gait is associated with gray matter (GM) density of the nucleus basalis of Meynert (nbM) and attention in people…Early synaptic loss and synaptic instability in a mouse model of prodromal Parkinson’s disease
Objective: In order to elucidate very early pathologis of Parkinson’s disease (PD), we focused on synaptic pathologies in a newly developed mouse model of prodromal…Knockdown of eEF1A2 reduced neuronal survival in a SH-SY5Y cellular model of Parkinson’s disease through the PI3K/Akt/mTOR pathway
Objective: To investigate whether eEF1A2 promotes neuronal survival through PI3K/Akt/mTOR pathway in a toxin-induced Parkinson’s disease model. Background: Parkinson’s disease is a common neurodegenerative disorder…Ubiquitin carboxyl-terminal hydrolase 1 (UCHL1) -mediated ubiquitination attributed to localization of Mortalin to mitochondria
Objective: The pathogenic mechanism of UCHL1 in PD remains unclear. In this study, we aimed to investigate the role of UCHL1 in the pathogenesis of…Relationship between cyclooxygenase-2 gene polymorphisms and Parkinson’s disease susceptibility in Chinese Han population
Objective: To investigate relationship between the cyclooxygenase-2 (COX-2) gene promoter region (rs20417, rs689466, rs689465) and 3'untranslated region (rs5275) polymorphisms with Parkinson’s disease (PD) susceptibility in…Frequency of the LRRK2 and GBA mutations in Russian population with Parkinson’s disease
Objective: To estimate the frequency of LRRK2 mutation (G2019S) and GBA mutations (N370S, L444P) and polymorphic variants (E326K, T369M) in PD and controls in the…Association between MAPT haplotype and hippocampal repetition suppression in Parkinson’s disease
Objective: We aimed to explore the relationship between the microtubule-associated tau gene (MAPT) haplotypes and response in the hippocampus to repeated stimuli in Parkinson’s disease…Bupropion causing misdiagnosis in brain dopamine transporter imaging for parkinsonism
Objective: To report long-lasting effects of bupropion on brain dopamine transporter (DAT) binding in a patient with depression and parkinsonism. Background: Striatal DAT imaging is…Brain responses evoked by thalamic and subthalamic deep brain stimulation
Objective: To reveal how the pattern of evoked responses differs between deep brain stimulation (DBS) of the ventral intermediate nucleus of the thalamus (VIM) and…Association of Olfaction dysfunction with Brain Microstructure in Prodromal Parkinson disease
Objective: Investigating the association between olfactory dysfunction and connectometry patterns in UPSIT-matched prodromal and PD patients. Background: Parkinson’s disease (PD) is a heterogeneous neurodegenerative disease…
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