Does the Basal Ganglia Dysfunction Affect Pisa Syndrome in Parkinson’s Disease?
Objective: We elucidated whether and how asymmetric basal ganglia dysfunction is associated with the generation of Pisa syndrome (PS) in Parkinson’s disease (PD). To assess…Classifying carriers of the G2019S mutation in the LRRK2 gene using MRI radiomics analysis
Objective: To use radiomics approach based on conventional MRI to classify carriers of LRRK2 mutation among non-manifesting first degree relatives of patients with PD. Background:…Gender Differences in Parkinson’s disease: Transcranial Magnetics Stimulation Study of Newly Diagnosed Drug-Naïve PD Patients
Objective: In early Parkinson’s disease (PD), functional changes may be detected in primary motor cortex (M1) using transcranial magnetic stimulation (TMS). We hypothesised that, if…Listen to the heart: Do loud vagal rhythms disharmonize the autonomic symphony in Parkinson’s disease patients with the LRRK2 mutation?
Objective: Assessment of cardiac autonomic function through standard and novel features of heart rate variability (HRV) in individuals who carry the G2019S mutation in the…Asymmetric olfactory deficit in H&Y stage-1 early onset Parkinson’s disease
Objective: To determine if the olfactory deficit in the early-stage Parkinson’s disease (PD) is asymmetric between the two hemispheres ipsilateral and contralateral to the onset…Evaluation of pain in Parkinson’s disease
Objective: To determine the prevalence of pain, types and characteristics of pain and the effect of pain on depression and daily living activities in early…Proteomic analysis of tear-fluid reveals disease-specific patterns in patients with Parkinson’s Disease
Objective: In this study, we set out to analyse changes of tear fluid (TF) proteome in Parkinson's Disease (PD) patients compared to age-matched controls (AMC)…Clinical differences between Parkinson’s disease motor phenotypes. Results from the COPPADIS Study Cohort
Objective: To describe the prevalence of different motor phenotypes in a large cohort of Parkinson´s disease (PD) patients and to analyze their clinical features in…Preliminary Study of Depression in Parkinson’s Disease with Diffusion Tensor Imaging
Objective: To explore the relationship between cognitive impairment in Parkinson’s Disease(PD) and the microstructure changes of brain region of interest(ROI) in diffusion tensor imaging(DTI). Background:…Impact of injection guidance techniques on the efficacy and safety of incobotulinumtoxinA for sialorrhea
Objective: SIAXI (NCT02091739), a pivotal double-blind, randomised, placebo-controlled study with an extension period (EP), assessed the efficacy and safety of incobotulinumtoxinA 75 or 100 U…
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