Altered intrinsic brain functional connectivity in drug-naïve Parkinson’s disease with LRRK2 mutation
Objective: This study aimed to compare the alterations in the cortico-striatal functional connectivity (FC) of drug-naïve Parkinson’s disease (PD) patients with the leucine-rich repeat kinase…Grey matter abnormalities associated with early cognitive decline in Parkinson’s disease
Objective: To identify patterns of grey matter (GM) abnormalities in patients with Parkinson's disease (PD) with different cognitive profiles. Background: Cognitive symptoms occur already in…Brain PET metabolic substrate of Impulse Control Disorders in Parkinson’s Disease
Objective: The aim of this study was to describe the cerebral metabolic PET substrate and related connectivity changes in Parkinson's disease patients with impulse control…Substantia nigra area evaluated by neuromelanin-sensitive MRI as an imaging biomarker of disease progression in Parkinson’s disease
Objective: to investigate the pattern of substantia nigra - neuromelanin (SN-NM) area loss and contrast ratio (CR) intensity changes in late-stage Parkinson’s disease (LSPD) patients,…The involvement of primary olfactory cortex in olfactory deficits in early-stage Parkinson’s disease
Objective: To determine if the primary olfactory cortex (POC) is involved in the olfactory deficits in early-stage Parkinson’s disease (PD) using functional magnetic resonance imaging (fMRI)…Patterns of Striatal DAT Binding Loss in a Progressing Parkinson Disease (PD) Cohort: Four year PPMI Follow-up
Objective: To evaluate within subject striatal changes in dopamine transporter (DAT) binding using 123-I Ioflupane SPECT in PD participants studied over four years in the…Normal “heart” in Parkinson’s disease: Is this a distinct clinical phenotype?
Objective: The aim of this study was to investigate whether non-motor manifestations of Parkinson’s disease (PD) differ between patients with normal and abnormal myocardial metaiodobenzylguanidine (MIBG)…Application of a Qualitative Model to Elucidate the Role of the Alpha-Synuclein System in Parkinson’s Disease.
Objective: Objective: In order to improve the understanding of the alpha-synuclein system and its role in Parkinson’s disease, Elan and Rosa collaborated in the development…Oral health-related quality of life and dental care among Parkinson’s disease patients and Care givers of South India.
Objective: The objective of the present study was to evaluate the oral health-related quality of life among patients and their caregivers with Parkinson's disease. Background: Parkinson's disease can severely…Analysis of related factors of occurrence of dementia in Parkinson’s disease using the application form of Parkinson’s disease provided by the specific diseases treatment research program of Ministry of Health, Labor and Welfare of Japan
Objective: Dementia has now been noticed as a significant non-motor symptom of Parkinson's disease (PD). We attempted to analyze the relation between the occurrence of…
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