Gait analysis as a complementary tool in the levodopa dose decision in Vascular Parkinson’s Disease
Objective: Evaluate the role of objective gait analysis in the decision of levodopa dose in VPD, in particular when compared to clinical assessment. Background: Vascular…Validation of actigraphy-derived sleep metrics in Parkinson’s disease (PD) patients and elderly controls, taking into account clinical and physiological status
Objective: To developed a novel sleep quantification method using raw actigraphy data from well characterized PD subjects and elderly controls with overnight PSG and home…Low frequency Deep Brain stimulation for Parkinson’s disease – Effect on freezing of gait.
Objective: Parkinson's disease patients who have undergone deep brain stimulation ( DBS) having freezing of gait do not show improvement with high frequency stimulation (…Closed Loop STN DBS for Tremor in Parkinson’s disease using a Neural or Kinematic Signal
Objective: Compare safety, tolerability, efficiency and efficacy of closed loop DBS (clDBS) of the subthalamic nucleus (STN) for resting tremor in Parkinson’s disease (PD) using…Fibroblasts Implanted in Internal Pallidum of Parkinsonian Macaques Exert L-Dopa-Sparing Activity
Objective: To assess the effects of autologous implantation of fibroblasts in the internal globus pallidus of dyskinetic MPTP-lesioned monkeys upon motor behaviour and L-DOPA response.…Parkinson Syndrome associated with inositol-1,4,5-triphosphate receptor antigen type 1 (ITPR1) antibodies
Objective: To illustrate an unusual clinical presentation of Parkinson´s disease (PD) that was effectively treated with immune adsorption. Background: Autoimmune mediated movement disorders may be…Psychiatric comorbidities are common in patients with Orthostatic Tremor
Objective: The objective of this study was to determine if there is a higher prevalence of psychiatric comorbidities, especially anxiety disorders, in orthostatic tremor (OT)…A survey-based analysis of abnormal movements in patients with Postural Tachycardia Syndrome (PoTS)
Objective: The aim of this study is to evaluate the characteristics of PoTS associated tremor. Background: Postural tachycardia syndrome (PoTS) is a dysautonomia most prevalent…Ataxia-Teleangiectasia-Mutated-Knock-Out mouse cerebellum shows significant reduction of calcium homeostasis factors
Objective: We aimed to identify sensitive and specific molecular markers of the cerebellar Purkinje neuron loss in Ataxia Teleangiectasia. Background: Ataxia teleangiectasia is an autosomal…Potential preclinical gait and balance markers for developing Fragile X-Associated Tremor/Ataxia Syndrome (FXTAS)
Objective: To conduct gait and balance “stress” tests including those with dual task (DT) cognitive interference which we hypothesized would reveal early motor impairments in…
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