Long-term levodopa therapy accelerates the circadian rhythm dysfunction in 6-OHDA rat model
Objective: We aimed to study the effect of L-DOPA on circadian rhythms in 6-OHDA lesioned rats, and to clarify whether the disturbance of the circadian…Self-rated burden grading of nonmotor symptoms identifies landmarks and subtypes of Parkinson’s disease: first report from a Moscow-Madrid-London collaboration
Objective: To describe clinical and imaging biomarkers of nonmotor symptoms burden (NMSB) as defined by NMS questionnaire (NMSQ) scores in a prospective international cohort study…Vmat2 heterozygote mice display motor dysfunction and progressive depressive-like behaviors
Objective: To assess motor and depressive behaviors in mice that are heterozygous for VMAT2 (VMAT2 HT). Background: Dopamine (DA) is compartmentalized by the vesicular monoamine…Association of nocturnal stridor with clinical features of patients with multiple system atrophy
Objective: To investigate the association between findings of night video-polysomnography and clinical feature of patients with multiple system atrophy (MSA). Background: Nocturnal sleep-related clinical sympotoms…Mutational analysis of COQ2 in Chinese patients with multiple-system atrophy
Objective: To investigate the involvement of COQ2 variants in Chinese sporadic cases with multiple-system atrophy. Background: Multiple-system atrophy (MSA) is a rapidly progressive neurodegenerative disease…Use of the Neuropsychiatric Inventory to Characterize the Course of Neuropsychiatric Symptoms in Progressive Supranuclear Palsy
Objective: The aim of this study was to determine the neuropsychiatric profile in our cohort of PSP patients and their dynamic changes over a follow-up…Are a „mathematical brain“ and early childhood adverse events possible risk factors that contribute to Progressive Supranuclear Palsy?
Objective: To evaluate possible risk factors for the development of Progressive Supranuclear Palsy (PSP). Background: Risk factors for the development of neurodegenerative brain disorders are…A PSP-like phenotype accompanies rapidly progressive dementia
Objective: We describe a patient with a progressive supranuclear palsy (PSP)-like phenotype and a rapidly progressive dementia, who was found to have an unknown CSF…Progressive supranuclear palsy presenting with corticobasal syndrome: a case report
Objective: Clinical description and interpretation of complementary diagnostic exams of a patient with probable PSP with corticobasal syndrome phenotype (PSP-CBS). Background: Underlying pathologies of CBS…Suicide in Parkinson disease
Objective: This study was carried out to analyze the suicide rate in our Parkinson disease (PD) population and review the clinical profiles of patients who…
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