Speech difficulties are linked to striatal dopaminergic deficits and cognitive decline in early de novo patients with Parkinson’s disease
Objective: To investigate whether speech difficulties are associated with striatal dopaminergic deficits and whether are linked to progression of symptoms in early de novo patients…Decreased Fronto-Parietal connection is associated with face pareidolia in Parkinson’s disease.
Objective: To investigate the neural mechanism of face pareidolia in Parkinson’s disease (PD) patients using resting state functional magnetic resonance imaging (rs-fMRI). Background: Face pareidolia…Dopamine depletion impairs gait automaticity by altering cortico-striatal and cerebellar processing in Parkinson’s disease
Objective: Investigating the role of dopaminergic medication on the neural mechanisms underlying lower limb motor automaticity during fMRI in 23 patients with PD that were…The role of phosphodiesterase 4 in sleep disturbances in Parkinson’s disease
Objective: We aimed to assess the association between phosphodiesterase 4 (PDE4) expression and sleep disturbances in vivo using combined multimodal magnetic resonance imaging (MRI) and…Clinical utility of visualization of Nigrosome-1 in patients with Parkinson’s disease
Objective: To determine the inter-rater reliability of Nigrosome-1 detection and its relation to asymmetry of clinical symptoms in Parkinson’s disease (PD). Background: Detection of Nigrosome-1…Syndenham’s chorea in Senegalese children: A case series
Objective: To describe clinical profile and treatment outcome of Sydenham’s chorea (SC) in children attending a tertiary care hospital in Dakar, Senegal. Background: SC is…First Report of Clinical Outcomes Resulting from Use of Directional Deep Brain Stimulation in Parkinson’s Disease and Essential Tremor
Objective: To evaluate clinical motor outcomes, the patient´s subjectively perceived benefit and the frequency of the use of directional lead stimulation in subjects with Essential tremor…Tremor as the first symptom reported by Parkinson’s disease patients is a predictor of future motor subtype and levodopa-induced dyskinesia.
Objective: To better delineate risk profiles for the development of levodopa-induced dyskinesia is an important effort that can help understand this phenomenon and could impact…MDS prodromal PD research criteria validation in two independent prospective cohorts
Objective: To evaluate the Movement Disorder Society prodromal Parkinson's disease criteria to two independent longitudinal studies Background: The MDS research criteria for prodromal Parkinson’s disease (PD)…Dr. Paula Coutinho’s Seminal Contributions to the Understanding of Machado-Joseph’s Disease
Objective: To recognize the contributions of Dr. Paula Coutinho to Neurology through her studies of Machado-Joseph’s disease (SCA3) Background: One of the unique opportunities in…
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