Lifelong daily workload and postural abnormalities in patients with Parkinson’s disease
Objective: To clarify the clinical relationship between lifelong daily workload and postural abnormalities of patients with Parkinson's disease (PD). Background: Recent clinical researches revealed postural…High-Resolution Manometry (HRM) in Parkinson’s Disease (PD)
Objective: To characterize esophageal symptoms in PD using high-resolution Manometry. Background: Dysphagia is common in PD; its etiology multifactorial and its management challenging. In a retrospective…Parkinson’s disease phenotype across different ethnic groups: Comparison of non-motor symptoms in patients living in the United Kingdom and Mexico
Objective: The aim is to compare and contrast clinical profiles between UK-White Caucasian (UK-WC), UK-Asian, UK-Black African Caribbean (UK-BAC) and Mexican people with Parkinson's disease…The Non-Motor Symptoms Questionnaire and Non-Motor Symptoms Scale for use in Sweden
Objective: To translate the Non-Motor Symptoms Questionnaire (NMSQ) and the Non-Motor Symptoms Scale (NMSS) into Swedish, and test their linguistic validity and user-friendliness. Background: Non-motor…Non-motor symptoms in a cross section of PD patients with varying degrees of smell loss
Objective: To establish whether patients with PD who have mild/moderate microsmia, severe microsmia or anosmia (as measured by the University of Pennsylvania Smell Identification Test…Phasic activity during non REM sleep
Objective: To describe the first reported case of behavioral and phasic neurophysiological activity during slow-wave sleep (SWS) in a patient with symtomatic REM sleep behavior…Viral-mediated oligodendroglial alpha-synuclein expression models multiple system atrophy
Objective: We aimed to develop AAV-based models of MSA Background: Multiple system atrophy (MSA) is a fatal neurodegenerative disorder characterized by a combination of autonomic…Gut Microbiota in Multiple System Atrophy
Objective: To investigate the gut microbiome and metabolome in MSA Background: Experimental models of prion-like cell-to-cell transfer of alpha-synuclein(AS) and its ability to spread from the…Evaluation of mitochondrial dysfunction in fibroblasts and iPSC-derived dopaminergic neurons of patients affected by Multiple System Atrophy
Objective: The aim of the present study is to investigate mitochondrial functioning in fibroblasts and iPSC-derived dopaminergic neurons of patients affected by Multiple System Atrophy…Anatomical predictors of survival in PSP: thalamic collapse towards the end of life
Objective: To correlate anatomical changes with time to death in PSP. Background: Many advances have been made in progressive supranuclear palsy (PSP) since it was first described…
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