Associations between Functional Networks and Temporal Discrimination Thresholds in Cervical Dystonia patients and their unaffected relatives
Objective: To investigate resting state functional networks across cervical dystonia patients and their unaffected relatives with and without abnormal temporal discrimination thresholds (TDTs) based on…Treatment of back pain in patient with extensor truncal dystonia with lumbar radiofrequency ablation (RFA)
Objective: Extensor truncal dystonia in majority of cases leads to significant low, mid back pain and discomfort secondary to muscle spasms and early degenerative spinal…Disease modeling for Perry syndrome using patient induced pluripotent stem cells
Objective: To develop a novel model of Perry syndrome using induced pluripotent stem cell (iPSC)-derived neurons. Background: Perry syndrome is a rare autosomal dominant disorder…3D image as a complimentary assist in patients with Parkinson’s disease
Objective: To assist patients with PD to overcome the fear of stair ascent and descent with help of 3D effect staircase Background: Since walking on…Effect of object size and obstacle avoidance on of Reach-to-Grasp Actions in Individuals with Parkinson’s disease
Objective: To investigate the effect of object size and obstacle on reach-to-grasp (RTG) actions in individuals Parkinson's disease (PD). Background: Previous studies reported impairments of…Double-blind, randomized, placebo-controlled, Phase III study (TOLEDO) to evaluate the efficacy of apomorphine subcutaneous infusion in reducing OFF time in Parkinson’s disease patients with motor fluctuations not well controlled on optimized conventional treatment
Objective: The TOLEDO Study (NCT02006121) is a prospective, randomized, multicenter, double-blind, Phase III trial undertaken to investigate the efficacy of apomorphine subcutaneous infusion (APO) compared…Disease severity is not predictive of the dose required for apomorphine sublingual film (APL-130277) to convert a patient with Parkinson’s disease(PD) from OFF to fully ON: Preliminary Results from a Phase III Study
Objective: To determine if baseline disease severity could be correlated to the effective dose of APL-130277 that was required to turn a patient with PD…Deep Learning in Objective Classification of Spontaneous Movement of Patients with Parkinson’s Disease Using Large-Scale Free-Living Sensor Data
Objective: Our goal was to classify spontaneous movement using a commercially available motion sensor in a clinically meaningful 3-/9-step discrete scale (SMS-3/SMS-9). Background: Brady-hypokinetic and dyskinetic…Deep brain stimulation in Parkinson’s disease: Outcome after more than nine years
Objective: The aim of this study is to examine the long-term effects of deep brain stimulation of the subthalamic nucleus (STN DBS) in Parkinson’s disease…Early morning OFF problems are common in PD patients attending a routine clinical appointment
Objective: To characterize early morning OFF problems in consecutive PD patients attending a routine clinical appointment. Background: In PD patients with motor fluctuations, total daily…
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