Multiple modality biomarker prediction of cognitive impairment in prospectively followed de novo Parkinson disease
Objective: To assess the neurobiological substrate of initial cognitive decline in Parkinson’s disease (PD) to inform patient management, clinical trial design, and development of treatments.…The clinical and neuroimaging analysis in hemifacial spasm with associated cranial neuropathy: retrospective case series study
Objective: To evaluate the clinical characteristics and neuroimaging findings observed in the association between hemifacial spasms (HFS) and other cranial neuropathy in a cohort of…FDG PET studies in the differential diagnose of atypical parkinsonism and dementia syndromes.
Objective: To describe the fluorodeoxyglucose (FDG) metabolic pattern and clinical features in patients with clinical diagnose of atypical parkinsonism such as Progressive Supranuclear Palsy (PSP),…DaTscan in clinical evaluation of Multiple System Atrophy
Objective: To explore accuracy of DaTscanTM Ioflupane I123 Injection (DaTscan) in a multiple system atrophy (MSA) cohort Background: There are isolated cases of normal DaTscan in neuropathologically confirmed MSA-cerebellar subtype (MSA-C)…The clinically-available anti-depressant mirtazapine alleviates both psychosis and dyskinesia in the MPTP-lesioned marmoset
Objective: To determine the effect of mirtazapine, a clinically-available anti-depressant, on psychosis and dyskinesia in Parkinson’s disease (PD). Background: Psychosis and dyskinesia cause significant morbidity…Impaired cerebellum to motor cortex associative plasticity in patients with spinocerebellar ataxia type 3
Objective: This study aims to investigate the associative plasticity induced by cerebellum to primary motor cortex (CB-->M1) corticocortical paired associative stimulation (PAS) in patients with…Dopamine replacement influences on postural motor learning in Parkinson disease
Objective: To determine if i) dopamine replacement affects general and sequence specific learning of a postural task in people with Parkinson disease (PD), and ii)…Sleep architecture in Parkinson´s disease and Parkinson’s disease associated dementia
Objective: To evaluate the differences in early sleep architecture between patients with Parkinson’s disease (PD) and Parkinson’s disease associated dementia (PDD). Background: Disorders of sleep…Cognition in the PREDICT-PD Cohort
Objective: To identify whether there is evidence for cognitive dysfunction in participants identified as being at higher risk of Parkinson’s disease (PD) using the PREDICT-PD…Fluency boost from walking in Parkinson’s disease
Objective: Examine the impact of a motor task on verbal fluency in individuals with Parkinson’s disease (PD) Background: Dual-tasking, in which individuals engage simultaneously in…
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