CR6-interacting factor1 Deficiency in Dopamine Neurons Triggers Early-onset Parkinsonism in Mice
Objective: One candidate is CR6-interacting factor1 (CRIF1), which controls translation and membrane insertion of 13 mitochondrial proteins involved in oxidative phosphorylation. Here we determined the…In silico predictive analytics: accelerating identification of potential disease-modifying compounds for Parkinson’s disease
Objective: To use an in silico screen to identify compounds that have potential to reduce α-synuclein (aSyn) oligomers and are amenable to drug repurposing for…Vitamin D in the Parkinson’s Associated Risk (PARS) Study
Objective: The purpose of this study was to evaluate vitamin D levels in a population at risk for developing Parkinson’s disease (PD). Background: Vitamin D…Putaminal Atrophy Gradient in X-linked Dystonia-Parkinsonism
Objective: To better understand striatal pathology in X-linked Dystonia-Parkinsonism (XDP) by combining T1 and Magnetization Transfer (MT) Imaging. Background: XDP is a neurodegenerative disorder characterized by…WILSON’S DISEASE: A Mongolian case
Objective: Objective: To determine the early clinical features that predict younger people who has Wilson’s disease(WD). Background: Backround: WD is fatal neurodegenerative disorder that is…Psycho-behavioral profile of Parkinson’s disease patients with RLS: a cross sectional-study
Objective: To determine whether RLS could be associated with a specific psycho-behavioral profile and ICDs in Parkinson's disease (PD). Background: Impulse Control Disorders (ICDs) have…Evaluating wearable sensors for objective measurement of motor features in Parkinson disease and Huntington disease – a pilot study
Objective: Evaluate the feasibility of wearable sensors in measuring motor features of individuals with PD, HD, prodromal HD, and controls in clinic and at home.…Assessment of new technology in deep brain stimulation technology: what are the anticipated benefits?
Objective: To assess the ability of directional DBS leads and stimulation field shaping to provide more precisely targeted therapy. Background: Deep brain stimulation (DBS) has…Antisense oligonucleotides containing amido-bridged nucleic acid downregulate SNCA expression and improve motor function in Parkinson’s disease mouse models.
Objective: In this study, we used gapmer-type antisense oligonucleotides (ASOs) containing amido-bridged nucleic acid (AmNA). ASO, short single-stranded stretches of DNA or RNA with complementary…Combined Motor and Cognitive Training Improves Motor and Cognitive Function in People with Parkinson’s Disease and Freezing of Gait
Objective: Investigate whether combined motor and cognitive training improves motor and cognitive function in people with PD and freezing of gait (FOG). Background: FOG affects…
- « Previous Page
- 1
- …
- 41
- 42
- 43
- 44
- 45
- …
- 155
- Next Page »