Screening of cognitive impairment in Huntington’s disease with the Parkinson’s Disease – Cognitive Rating Scale (PD-CRS)
Objective: To explore the psychometric properties of the PD-CRS as compared to two commonly used measures (the MMSE and the UHDRS Cognitive score) for detecting…Longitudinal Study of Cortico-Striatal Functional Connectivity in Huntington’s Disease Measured with High-Field Functional MRI.
Objective: To assessed functional connectivity by using functional Magnetic Resonance Imaging (fMRI) at 7 Tesla as baseline and one year thereafter. Background: Our previous study…Evidence-based Brazilian Physicaltherapy Guideline for Huntington´s Disease
Objective: Identify the Evidence based Physicaltherapy available for HD and provide recommendations to physicians Background: In Huntington’s Disease (HD) Chorea is usually presented in any phase…Disease-modification in Translational Models of Parkinson’s disease by the Rho Kinase Inhibitor Fasudil
Objective: To evaluate the therapeutic potential of the Rho Kinase (ROCK) inhibitor Fasudil in translational models of Parkinson’s disease (PD). Background: There is still a…Analysis of serum non-mercaptoalbumin in patients with Parkinson’s disease
Objective: It is well known that the oxidative stress might be associated with the pathomechanisms of Parkinson’s disease (PD). In this study, we assessed serum…Feasibility and Safety of Multisite Tissue and Biofluid Sampling for Alpha-Synuclein in Parkinson’s Disease: The Systemic Synuclein Sampling Study (S4)
Objective: The S4 study aims to characterize the distribution of alpha-synuclein (aSyn) pathology in multiple tissues and body fluids within the same Parkinson’s disease (PD)…Evaluation of spike sorting algorithms applied to artificial spikes and to spikes recorded from the Subthalamic Nucleus of PD patients
Objective: To evaluate the variability in spike sorting results using different clustering algorithms Background: Extracellular currents recorded from the Subthalamic Nucleus (STN) of PD patients,…Anti-synuclein alpha antibodies and IL-1β at Parkinson Disease (PD).
Objective: Determine a correlation between the levels of anti-synuclein alpha antibodies and IL-1β at serum and CSF of patients with PD. Background: PD is a…Neuroprotective effect of α-Mangostin in restoration mitochondrial function in MPTP-Induced Parkinson’s disease in mice
Objective: The aim of the present study was to explore the protective effect of alpha-mangostin against mitochondrial oxidative stress in MPTP treated mice. Background: It…Freezing of gait in Parkinson’s disease consists of unique pressure-based gait phase transitions
Objective: To develop a method to detect freezing of gait in real time Background: Freezing of gait (FOG) is a major debilitating symptom and cause…
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