Cognitive Mechanisms of Visual Dysfunction in Non-Demented PD Patients (PD-ND)
Objective: To conduct a comprehensive assessment of visual processing in PD-ND, including tests of low-level vision sensitive to retinal pathology, high-level object/spatial vision reflecting ventral/dorsal…Autonomic Dysfunction in Early Parkinson’s Disease: Cross-Sectional Study in Hoehn and Yahr Stage 1
Objective: To define frequency, severity and predictors of dysautonomia in patients with Parkinson's disease(PD) at the stage of hemiparkinsonism with disease duration less than 2…The impact of divided attention in dual task conditions on drooling in Parkinson’s Disease (PD): a pilot study
Objective: To investigate whether frequency of saliva swallows reduced, and drooling severity and frequency increased, when people with PD engaged in a distracting cognitively demanding…Differential effects of ventral or dorsal predominant dopaminerjic denervation of striatum on development of dopamine dysregulation syndrome and punding in a rat model of parkinsonism
Objective: To model and assess the differential effects of ventral or dorsal predominant dopaminergic denervation of striatum on development of impulsive compulsive behaviors (ICB) in…Subthalamic nucleus local field potential activity during the sleep-wake cycle
Objective: Characterize changes in Subthalamic Nucleus local field potential (STN LFP) activity related to stages of the sleep-wake cycle. Background: Deep brain stimulation (DBS) devices…REM sleep behavior disorder: Is it useful to differentiate between Parkinson disease and Progressive Supranuclear Palsy?
Objective: To determine the prevalence of rapid eye movement (REM) sleep behavior disorder (RBD) in autopsy confirmed Parkinson disease (PD) and Progressive Supranuclear Palsy (PSP).…Profound reduction of DAT-SPECT signal in multiple system atrophy (MSA)
Objective: To evaluate the extent of degeneration in dopamine nerve terminal in striatum in the patients with MSA-P and MSA-C, and to compare the progression…Neuroactive steroids reverse the dopaminergic neurotransmission defectiveness in chronic hepatic (HE) encephalopathy: a possible involvement in HE related parkinsonism
Objective: In the present study, we describe the changes of the dopaminergic system occurring in the cirrhotic rats and concomitantly we investigated the effect of…Development of a Clinician-reported Screening Tool to Identify Patients with Parkinson’s disease inadequately controlled on oral medications
Objective: To identify key clinical indicators for Parkinson disease (PD) patients inadequately controlled with oral medications or eligible for device-aided treatments. Background: Identifying patients with…Cognitive profiling in patients with Parkinson’s disease, multiple system atrophy and progressive supranuclear palsy: a 15-month longitudinal study
Objective: To characterize the progression of cognitive decline and compare the neuropsychological 15-month profile across PSP, MSA and PD. Background: Cognitive impairments are frequently reported in…
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