Disease-modifying effect of Zonisamide with the induction of BDNF and TrkB expression
Objective: To evaluate to predictors of the disease-modifying effect of drugs on Parkinson’s disease (DM-PD) according to long-term therapeutic investigation, especially regarding the non-dopaminergic agent…Towards Responsive Deep Brain Stimulation for Medically Refractory Freezing of Gait in Parkinson’s Disease
Objective: Medically refractory FoG presents an unmet and pressing need to develop novel therapeutic strategies. We seek to describe the electrophysiology of the pedunculopontine nucleus…Deep Brain Stimulation of Subthalamic Nucleus Selectively Modulates Striato-Thalamo-Cortical Circuit in Parkinson’s Disease: a Systematic Review and ALE Meta-analysis
Objective: To investigate pooled effect of STN-DBS effect on brain activity in Parkinson’s disease (PD), and to address the result inconsistency across previous functional image studies.…F-18-DOPA-PET predicts impulsive behavior under dopaminergic therapy in Parkinson patients
Objective: The aim of this study is to investigate the influence of the intensity of dopaminergic projections to the ventral striatum (VS) measured with F-18-DOPA-PET…Distinct pattern of striatal dopaminergic depletion in patients with parkin mutation
Objective: As a pilot study, this study was aimed to perform the detailed analysis of the striatal DAT density in patients with early-onset Parkinson's disease…SPECT imaging of striatal DAT availability in Parkinson’s: changes over time and relevance to dyskinesias
Objective: This study was designed to explore in Parkinson’s disease (PD) the role of dopamine transporter (DAT)-specific single photon emission computed tomography (SPECT) imaging as a…Utility of DaTscan Imaging in Differentiating Drug Induced Parkinsonism from IPD and Other Forms of Parkinsonism
Objective: To determine clinical correlates which differentiate drug induced Parkinsonism (DIP) from IPD and other forms of Parkinsonism using DaT-SPECT imaging. Background: DaT-SPECT imaging is…The brain plasticity for controlling reach-to-grasp functions of Parkinson’s disease
Objective: To investigate the brain plasticity for controlling the dominant and non-dominant hand muscles and reach-to-grasp (RTG) functions in Parkinson’s disease (PD). Background: Previous studies…Assessing Nigral Functional Connectivity in Parkinson’s Disease with Resting State Functional MRI
Objective: To evaluate functional connectivity of SN with basal ganglia and motor cortex in Parkinson’s disease (PD) using resting state functional MRI (RS fMRI). Background:…Globus Pallidus and Pedunculopontine Nucleus Oscillations during Executed and Imagined Gait in Patient with Parkinson’s Disease and Freezing of Gait Symptoms.
Objective: To explore neurophysiological markers of intentional executed and imagined movement in both Globus Pallidus Internus (Gpi) and Pedunculopontine Nucleus (PPN) in patients with Parkinson’s…
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