Botulinum Neurotoxin (BoNT) for treatment of functional (psychogenic) jerky movement disorders: a randomized placebo-controlled clinical trial
Objective: To assess the effectiveness of botulinum neurotoxin (BonT) in patients with functional jerky movement disorders Background: At least 2–9% of patients seen in movement…Treatment of secondary movement disorders related to midbrain cavernomas
Objective: To evaluate possible efficacy and safety of standard antiparkinsonian drugs (levodopa formulations, amantadine) in patients with symptomatic midbrain cavernomas (haemorhage and/or surgery) and secondary…Essential Tremor and Depression
Objective: To determine if depression and neuropsychiatric symptoms are more prevalent in patients with essential tremor (ET) compared with non-ET controls and if so, to establish…Forehead Tremor: a clinical presentation of ocular Myasthenia Gravis?
Objective: The case of a patient with seropositive Myasthenia gravis (MG), presenting with forehead tremor, is reported. Background: The clinical presentation of MG with involuntary movements…Targeting the intracellular localization of Ataxin-3 as novel treatment strategy for Spinocerebellar Ataxia Type 3
Objective: Spinocerebellar ataxia type 3 (SCA3) or Machado-Joseph disease (MJD) is an autosomal-dominantly inherited neurodegenerative disorder caused by a CAG expansion in the ATXN3 gene…TANDEM REPEATS BEYOND THE CLINICAL DIAGNOSIS IN ADCAs
Objective: To present observations on abnormal expansion in both allele in ADCAs. Background: Use of expansion in tandem repeats is restricted to only disease diagnosis…Eye Movements in Huntington Disease Like 2
Objective: ObjectiveTo determine if eye movements are preserved in Huntington Disease-Like 2 (HDL2) and if this can be used to differentiate HDL2 from Huntington Disease…Multiple modality biomarker prediction of cognitive impairment in prospectively followed de novo Parkinson disease
Objective: To assess the neurobiological substrate of initial cognitive decline in Parkinson’s disease (PD) to inform patient management, clinical trial design, and development of treatments.…The clinical and neuroimaging analysis in hemifacial spasm with associated cranial neuropathy: retrospective case series study
Objective: To evaluate the clinical characteristics and neuroimaging findings observed in the association between hemifacial spasms (HFS) and other cranial neuropathy in a cohort of…FDG PET studies in the differential diagnose of atypical parkinsonism and dementia syndromes.
Objective: To describe the fluorodeoxyglucose (FDG) metabolic pattern and clinical features in patients with clinical diagnose of atypical parkinsonism such as Progressive Supranuclear Palsy (PSP),…
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