Grey matter abnormalities associated with early cognitive decline in Parkinson’s disease
Objective: To identify patterns of grey matter (GM) abnormalities in patients with Parkinson's disease (PD) with different cognitive profiles. Background: Cognitive symptoms occur already in…Brain PET metabolic substrate of Impulse Control Disorders in Parkinson’s Disease
Objective: The aim of this study was to describe the cerebral metabolic PET substrate and related connectivity changes in Parkinson's disease patients with impulse control…Substantia nigra area evaluated by neuromelanin-sensitive MRI as an imaging biomarker of disease progression in Parkinson’s disease
Objective: to investigate the pattern of substantia nigra - neuromelanin (SN-NM) area loss and contrast ratio (CR) intensity changes in late-stage Parkinson’s disease (LSPD) patients,…The involvement of primary olfactory cortex in olfactory deficits in early-stage Parkinson’s disease
Objective: To determine if the primary olfactory cortex (POC) is involved in the olfactory deficits in early-stage Parkinson’s disease (PD) using functional magnetic resonance imaging (fMRI)…Patterns of Striatal DAT Binding Loss in a Progressing Parkinson Disease (PD) Cohort: Four year PPMI Follow-up
Objective: To evaluate within subject striatal changes in dopamine transporter (DAT) binding using 123-I Ioflupane SPECT in PD participants studied over four years in the…Prof. Wadia’s contributions to neurology and SCA2
Objective: To present a review of the seminal contributions of Professor Wadia to neurology, in particular the first description of SCA2. Background: Spinocerebellar ataxia type…Diagnostic utility of regional [18F]AV-1451 tau-PET measurements in PSP
Objective: To determine the diagnostic utility of regional subcortical [18F]AV-1451 tau-PET measurements to differentiate progressive supranuclear palsy (PSP) from age-matched controls and Alzheimer’s dementia patients.…Occupational trichloroethylene exposure and Parkinson’s disease risk
Objective: To assess whether occupational exposure to the solvent trichloroethylene (TCE) is associated with increased risk of Parkinson's disease (PD). Background: Severe solvent intoxication can…Tonsillectomy and risk of Parkinson’s disease: A Danish nationwide population-based cohort study
Objective: To our knowledge, no studies have examined whether the lymphoid tissue of the tonsils are involved PD, or whether tonsillectomy modifies the risk of PD.…Circadian and Homeostatic Modulation of Multi-unit Activity in Dopaminergic and Striatal Structures
Objective: The aim of this study is to investigate the circadian and homeostatic modulation of the multi-unit activity of dopamineric and striatal neuronal structures. Background:…
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