Regional differences may influence the drivers of change in Toronto Western Spasmodic Rating Scale (TWSTRS) scores following botulinum toxin treatment: Analysis of an international observational study
Objective: Investigate the drivers for change in Toronto Western Spasmodic Rating Scale (TWSTRS) scores in subjects with cervical dystonia (CD) following a single injection of…Intermuscular and cortico-muscular coherence of patients with writer’s cramp
Objective: We present our pilot data on the Intermuscular coherence (IMC) and cortico-muscular coherence (CMC) pattern in writer’s cramp (WC) patients, healthy participants and patients…Clinical Relevance of Treatment With OnabotulinumtoxinA in Patients With Cervical Dystonia: Results From the CD Probe Study
Objective: To explore minimal clinically important change perceived by patients as beneficial by the Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS) using data from the…Mirror dysonia in writer`s aramp: a study with advanced multi-channel micro-electrode recording EMG system
Objective: To differentiate between those with concordant(C) and discordant (D) MMs in WC, in order to establish that there is a quantifiable difference between these…Intracranial calcifications and dystonia associated with a novel deletion encompassing SLC20A2 and THAP1
Objective: Describe a case of dystonia and intracranial calcifications associated with a deletion within 8p11.21 Background: Multiple genes located within chromosome 8p11.21 are associated with…Motor Heterogeneity in Parkinson’s Disease: A Bayesian Perspective
Objective: To identify motor symptom subtypes in idiopathic Parkinson’s disease (PD) using a Bayesian analytic approach to latent profile analysis. Background: Several subtypes of Parkinson’s…Elevated GM3 Plasma Concentration in Idiopathic Parkinson’s Disease: a Lipidomics Analysis
Objective: To test the association between plasma lipids and Parkinson disease (PD) diagnosis. Background: PD is a common neurodegenerative disease whose pathological hallmark is the…Epidemiological profile and challenges of a reference public center for the treatment of neurological conditions using botulinum toxin type A: experience of a North-eastern center in Brazil.
Objective: To identify the epidemiological profile of patients treated with botulinum toxin type A (BTA) in a tertiary clinic in Brazil. Background: BTA is used to…Nilotinib differentially affects oligomeric α-synuclein and reduces phosphorylated neurofilaments and motor symptoms in Parkinson’s disease with dementia and Lewy body dementia
Objective: This is a retrospective biomarker study of an open-label clinical study to examine the safety and efficacy of lower doses (<50% of CML dose)…INTREPID Trial: A Prospective, Double blinded, Multi-center Randomized Controlled Trial Evaluating Deep Brain Stimulation with a New Multiple-Source, Constant-Current Rechargeable System in Parkinson’s Disease
Objective: The objective of the INTREPID clinical trial is to assess the improvement in motor function and quality of life in patients with advanced, levodopa-responsive…
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