Epidemiological profile and challenges of a reference public center for the treatment of neurological conditions using botulinum toxin type A: experience of a North-eastern center in Brazil.
Objective: To identify the epidemiological profile of patients treated with botulinum toxin type A (BTA) in a tertiary clinic in Brazil. Background: BTA is used to…Nilotinib differentially affects oligomeric α-synuclein and reduces phosphorylated neurofilaments and motor symptoms in Parkinson’s disease with dementia and Lewy body dementia
Objective: This is a retrospective biomarker study of an open-label clinical study to examine the safety and efficacy of lower doses (<50% of CML dose)…INTREPID Trial: A Prospective, Double blinded, Multi-center Randomized Controlled Trial Evaluating Deep Brain Stimulation with a New Multiple-Source, Constant-Current Rechargeable System in Parkinson’s Disease
Objective: The objective of the INTREPID clinical trial is to assess the improvement in motor function and quality of life in patients with advanced, levodopa-responsive…Intensive Short-Term Dance Intervention in Parkinson’s Disease
Objective: To evaluate changes in motor symptoms and quality of life for people with Parkinson’s disease (PD) as a result of an intensive short-term dance intervention. …Virtual research visits in individuals with Parkinson disease enrolled in a clinical trial: REACT-PD Study Interim Analysis
Objective: To demonstrate the feasibility, reliability, and value of conducting web-based clinical trial assessments in individuals with Parkinson disease (PD). Background: Increasing interest has been…Focused ultrasound subthalamotomy for Parkinson’s disease: A pilot study
Objective: To evaluate feasibility, safety and effectiveness of unilateral subthalamotomy performed with MRIgHIFU to treat the cardinal motor features of PD Background: Ablative functional neurosurgery for…Movement disorder specialists’ determination of eligibility for device aided treatment in advanced Parkinson’s disease: Results from the OBSERVE-PD study
Objective: To characterize the clinical and non-clinical features of ‘advanced’ PD patients considered to be eligible or ineligible for device-aided treatment (DAT) options by movement…The occurrence of dopamine-responsive and dopamine-resistant resting tremor in Parkinson’s disease
Objective: To investigate dopamine-responsiveness of resting tremor in Parkinson’s disease Background: Unlike the core Parkinson motor symptom, bradykinesia, resting tremor has a variable response to…A novel paradigm of variable frequency deep brain stimulation to improve freezing of gait in Parkinson’s disease
Objective: To determine the effects of a novel deep brain stimulation (DBS) paradigm of combining high and low frequency stimulation in varying patterns (VFS) for…Evolution in Dopamine Transporter (DaT) Scan Utilization Patterns and its Effect on Treatment Decisions: Results of the Next 200 Scans
Objective: To describe further changes in DaT scan utilization and its influence on management following our initial experience. Background: We previously reported our DaT scan…
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