Cerebello-cortical loops differ between Essential-, Parkinsonian- and voluntary tremor
Objective: Topographical comparison of subcortico-cortical oscillating loops between different tremors. Background: Cerebellum and cortical motor regions are involved in Essential, Parkinsonian and voluntary tremor, three oscillatory motor…TETRAS applicability and study design in randomized, placebo controlled clinical trial of Cav3 modulation for essential tremor patients.
Objective: We will study CX-8998, a selective Cav3 antagonist with safety data in 194 patients, in the treatment of ET. Few large controlled ET trials…SPG7 related spastic ataxia differs according to the presence of the A510V variant
Objective: To characterize phenotype-genotype correlation in patients with two SPG7 variants, supported by a post mortem study. Background: The SPG7 gene was the first identified…The spectrum of composite autonomic severity score in SCA1, SCA2 and SCA3 patients
Objective: To analyze composite autonomic severity score in patients of spinocerebellar ataxia types 1, 2 and 3. Background: Spinocerebellar ataxia (SCA) is a progressive neurodegenerative…Steroid-responsive encephalopathy with associated thyroiditis (SREAT) presenting with pure cerebellar ataxia
Objective: To describe two patients with SREAT presenting with progressive cerebellar ataxia. Background: SREAT or Hashimoto’s encephalopathy is an autoimmune encephalopathy typically presenting with rapidly…Metabolic pattern of acute hemichorea associated with contralateral carotid stenosis
Objective: To investigate the metabolic pattern of acute hemichorea associated with contralateral carotid artery stenosis and no lesion on structural brain imaging, using brain 18F-FDG-PET.…Neurofilament light chain levels in cerebrospinal fluid do not discriminate between patients with prion disease and mimics
Objective: To determine whether levels of neurofilament light chain (NFL) in cerebrospinal fluid (CSF) are useful to discriminate between patients with prion disease (PrD) and…Asymmetric Orthostaic Myoclonus – A Case Series
Objective: To present the first case series of asymmetric orthostatic myoclnus and its reversibility along with the improvement of the underlying disease Background: Orthostatic myoclonus…In vivo evaluation of tau and amyloid pathology in Corticobasal Syndrome
Objective: To assess in vivo, with molecular imaging the brain distribution of tau aggregates ([18F]AV1451 PET) and β-amyloid depositions ([18F]AV45 PET) in patients with Corticobasal…Neuroticism and depression is associated with impulse control disorder in Parkinson’s disease: a controlled study
Objective: Cross-sectional assessment of personality trait, impulsivity, depression and anxiety collected prospectively in Parkinson’s disease (PD) with impulse control disorders (PD-ICD) compared to a matched…
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