Parkinson ‘ s disease and Peripheral Nervous System : Wax and Waning Non-motor offs and Levodopa-use Topics
Objective: To relate the non-motor offs theory , sensory signs and levodopa use with neurophysiiology terms in PD Background: Peripheral Nervous System disease concept in…Serum soluble transferrin receptor levels correlate with the Hoehn & Yahr stage of Parkinson disease progression
Objective: To test whether levels of soluble transferrin receptor (sTfR) in the serum of Parkinson disease (PD) patients are correlated with the progression of the disease…New device HANABI (HANdai Amyloid Burst Inducer) is a rapid and sensitive detecting system of α synuclein fibril in CSF from Parkinson’s disease patients
Objective: Early diagnosis for PD is disturbed by the lack of sensitive and objective detection of accumulated αSyn in the patient’s brain. Recently, Real-Time Quaking-Induced…Objective identification of freezing of gait in Parkinson’s disease patients using a triaxial accelerometer
Objective: The aim of this study is to objectively detect and quantify freezing of gait (FOG) in Parkinson’s disease (PD) patients during everyday activities. Background:…Goal-Directed Movement in Idiopathic Parkinson’s Disease and the effect of Parkin Mutations
Objective: To investigate goal-directed behavior in people with Parkinson’s disease (with and without Parkin mutations) and healthy controls using a computer based task. Background: In…Development of nano-formulation containing crocetin for the protective and beneficial effect against 6-hydroxydopamine induced Parkinson’s disease model via altered the genetic backgrounds
Objective: Parkinson’s disease (PD) induced by the interaction between the number of factors viz., aging, genetics toxins, mitochondrial deformity and oxidative stress. Various evidences suggest…Genetic knock-down of HDAC4 attenuates rotenone-induced abnormal expression of α-synuclein by affecting autophagic flux in SH-SY5Y Cells
Objective: To assess whether histone deacetylase 4 (HDAC4) is related to the abnormal expression of α-synuclein (α-syn) via the autophagy pathway. Background: The overexpression and…Glut-1 deficiency: a case report
Objective: To report the case of a patient with refractory seizures who was diagnosed with Glut-1 deficiency. Background: Although Epilepsy is commonly diagnosed by child…Non-motor symptoms in ACDY5-associated disease
Objective: To describe non-motor symptoms in a case of ACDY5-associated disease. Background: The hereditary dyskinesia syndrome caused by an ACDY5 mutation was first described in…Impaired cerebral and systemic endothelial dysfunction in patients with restless legs syndrome
Objective: In this study, we aim to determine whether an association between RLS and endothelial dysfunction exists. Background: Restless legs syndrome (RLS) is a sleep…
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