Recognition of parkinsonism in African Americans in a community-based sample
Objective: To investigate recognition of parkinsonism in African Americans (AA) in a community-based sample in Chicago. Background: Prior studies suggest that the manifestation of parkinsonism…A novel interdisciplinary palliative care clinic for advanced Parkinson’s disease and Parkinsonian syndromes
Objective: We describe a novel interdisciplinary clinic for advanced Parkinson's disease (PD) and Parkinsonian syndromes incorporating palliative care principles to improve quality of life. Background:…Group meetings for newly diagnosed Parkinson’s disease patients and their spouses: A preliminary experience
Objective: To estimate the contribution of a group meeting for newly diagnosed PD patients and their spouses. Background: Parkinson's disease (PD) is a common neurodegenerative…Impact of self-efficacy education on physical and psychosocial functioning in newly-diagnosed Parkinson patients
Objective: To evaluate whether this program improves physical and psychosocial functioning in newly-diagnosed persons with Parkinson's disease (PWP) over the 12-month period of the intervention…sFIDA: A sensitive diagnostic assay for quantification of α-synuclein aggregates
Objective: Optimizing of our sFIDA (surface-based fluorescence intensity distribution analysis) assay for specific detection and quantification of single α-synuclein aggregates. Background: Parkinson's disease (PD) is…Sensor based gait analysis: Diagnostic application for apomorphine titration
Objective: The goal of the present study was to quantify individual gait changes by eGaIT during the standardized titration test for subcutaneous apomorphine treatment. Background:…Novel THAP1 missense mutation leading to focal and segmental dystonia
Objective: We have identified a novel heterozygous missense mutation in THAP1 (DYT6 locus) in a patient suffering from craniocervical and upper limb dystonia. We describe…Familial SPG17/distal hereditary motor neuropathy type V– Complicated hereditary spastic paraplegia with many faces
Objective: We present the clinical and genetic results of a SPG17 family with a vast intrafamilial phenotype from subclinical signs to a severe and rapidly…Reduced thalamo-cortical functional connectivity in asymptomatic LRRK2 mutation carriers
Objective: To characterize MRI functional patterns during resting state in asymptomatic LRRK2 mutation carriers. Background: Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene are…Investigation into the genetic etiology in South African Parkinson’s disease patients
Objective: To investigate the genetic etiology in a group of South Africa Parkinson's disease (PD) patients. Background: The genetic etiology of PD is complex and…
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