Are people with Parkinson’s disease living in care homes in the UK underserved? Identifying models of care and barriers to care access
Objective: To conduct a nationwide online survey of Parkinson's disease nurse specialists (PDNS) and Parkinson's UK information staff to gain insight into current models of…Evaluation of stigmatization and quality of life before and after botulinum toxin treatment in hemifacial spasm
Objective: Hemifacial spasm (HFS) is a chronic disease that is characterized by involuntary tonic and clonic contractions of the muscles innervated by the ipsilateral facial…A strategy to classify Parkinson’s disease patients with dyskinesia: The analysis of center of pressure with impact of cognitive loading
Objective: To propose a strategy to classify Parkinson's disease (PD) with/without dyskinesia by analyzing center of pressure (CoP) with impact of cognitive loading. Background: Cognitive…Reliability and responsiveness of in-clinic and at-home app-based bradykinesia assessment
Objective: To evaluate reliability and responsiveness of an objective app-based bradykinesia assessment tool in the clinic and at home and to compare it to clinical…Computational analysis of expression profiling data in a neuronal model of X-linked dystonia-parkinsonism
Objective: To identify differentially expressed genes and enriched gene sets in a neuronal model of X-linked dystonia-parkinsonism (XDP, DYT3). Background: The putative dysfunctional gene in…Clinical and genetic analyses in a cohort of the Taiwanese patients with apparently sporadic pure spastic paraplegia
Objective: To systemically screen some common spastic paraplegia genes (SPG) in the Taiwanese patients with apparently sporadic pure spastic paraplegia. Background: Hereditary spastic paraplegias (HSP)…No RAB39B gene mutations in Chinese familial Parkinson’s disease
Objective: To validate the susceptibility to familial PD patients caused by RAB39B in Chinese Han population. Background: Recently, RAB39B mutations c.503C>A and c.574G>A have been…LRRK2 G2019S mutation carrier with an unusual phenotype: Progressive logopenic aphasia
Objective: To report the case of a patient carrying the G2019S mutation of the LRRK2 gene presenting with progressive logopenic aphasia and not manifesting PD…Next-generation profiling to identify the molecular etiology of Parkinson’s disease dementia
Objective: To identify novel gene regulatory events associated with Parkinson's disease with dementia (PD-D). Background: PD-D is associated with the spread of degenerative pathology to…Longitudinal evaluation of motor and non motor symptoms among LRRK2 risk variants
Objective: To evaluate the clinical characteristics and progression of Parkinson's disease (PD) in patients with Asian-related LRRK2 variants, G2385R, R1628P and S1647T. Methods: A total…
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