Reach-to-grasp impairments of both hands in individuals with Parkinson’s disease
Objective: To compare the reach-to-grasp (RTG) planning, kinematics and coordination of the less- (left) and more affected (right) hand in Individuals with Parkinson's disease (PD)…Micro-RNA in cerebrospinal fluid as a biomarker for early diagnosis, differential diagnosis and prognostic marker in Parkinson’s disease
Objective: This study aims to identify specific micro-RNA (miRNA) patterns in cerebrospinal fluid (CSF) of patients with Parkinson's disease (PD) and to compare them with…Histone deacetylase 4 is regulated by microRNA 128 in SH-SY5Y cells of Parkinson’s disease
Objective: To explore the mechanisms and regulating effects of microRNA 128 in Parkinson's disease (PD). Background: PD is the second common progressive neurodegenerative disorder characterized…Exploring aging-VMAT2 gene-rotenone interactions in a cell model for Parkinson’s disease
Objective: To develop a Parkinson's disease (PD) model based on aging, vesicular monoamine transporter 2 (VMAT2) gene susceptibility and chronic rotenone exposure in SK-N-SH cell,…Falls in Parkinson’s disease: Beware the short, slow steps
Objective: To determine if step length influence falls in Parkinson's disease (PD) patients. Background: Falls are major cause of disability in PD. The objective of…Altered glutamate response and calcium dynamics in iPSC derived striatal neurons from XDP-patients
Objective: Our objective was to generate an in vitro model of XDP based on striatal neurons differentiated from induced pluripotent stem cells (iPSC), followed by…A randomized, double-blind, placebo-controlled trial of deutetrabenazine for the treatment of tardive dyskinesia (ARM-TD)
Objective: To determine the efficacy and safety of deutetrabenazine (DTB) as a treatment for tardive dyskinesia (TD). Background: There is no approved treatment for TD,…Psychiatric profile in functional (psychogenic) jerky movement disorders
Objective: To systematically assess the psychiatric profile in functional jerky movement disorders. Background: Less and less emphasis is currently placed on psychopathology in functional neurologic…Augmentation and impulse control disorders in restless legs syndrome – Coexistence or association?
Objective: To assess the frequency of impulse control disorders (ICDs) in patients with restless legs syndrome (RLS) with and without augmentation under dopaminergic therapy. Background:…Children with idiopathic tics reveal additional features of hyperkinetic movement disorders
Objective: To investigate whether children with tics reveal features of additional hyperkinetic movement disorders. Background: The patho-physiology for idiopathic tic disorders is unknown, although underlying…
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