Single versus multiple microelectrode recordings (MER) in STN-DBS-surgery for PD: A randomized double-blind controlled trial
Objective: To evaluate whether using multiple versus single MER-guidance peroperatively influence improvement of motor symptoms by STN-DBS in advanced PD. Background: It is well established…A pilot study of horizontal current steering with chronically implanted segmented electrodes for STN-DBS in Parkinson’s disease
Objective: To evaluate the effect of horizontal current steering using a chronically implanted segmented lead and multiple independent current source technology on clinical effect and…DBS of the STN in 44 patients with Parkinson’s disease – Radiological and clinical outcome
Objective: Precision in implantation of deep brain stimulation (DBS) electrodes relies on systematic interdisciplinary planning and intra-operative testing and needs to be discussed along with…Bacterial biofilm formation on neurostimulation systems
Objective: The aim of this study is to identify specifically the DNA of bacterial biofilm on neurostimulation systems using polymerase chain reaction (PCR). Background: Bacterial…Thalamic-subthalamic deep brain stimulation for refractory orthostatic tremor: A report of 3 cases
Objective: To report a case series of thalamic-subthalamic deep brain stimulation for the treatment of refractory orthostatic tremor. Background: Orthostatic tremor (OT) is a rare,…Treatment of lipopolysaccharide-induced parkinsonism
Objective: This single case report of levodopa-responsive parkinsonism, caused by an accidental systemic contamination with 10 microgram lipopolysaccharides (LPS) from Salmonella minnesota, describes the treatment…Influence of onset age on the progression of non-motor symptoms in Parkinson’s disease: A prospective study from Southwest China
Objective: To explore the influence of onset age on the progression of non-motor symptoms (NMS) in Parkinson's disease. Background: NMS are gaining increasing relevance in…Motor rigidity selectively associates with impaired odor identification in Parkinson’s disease
Objective: To investigate the relationship between impairments of the cardinal motor symptoms and odor identification deficits in Parkinson's disease (PD). Background: Although hyposmia has been…Faithful SGCE imprinting in iPSC-derived cortical neurons: An endogenous model system of myoclonus-dystonia
Objective: To test the potential of induced pluripotent stem cell (iPSC)-derived cortical neurons from Myoclonus-dystonia (M-D) patients when studying specific epigenetic and brain-specific aspects of…Incidence of dynamic aphasia in progressive supranuclear palsy
Objective: To evaluate of Incidence of dynamic aphasia in Progressive supranuclear palsy. Background: Progressive supranuclear palsy (PSP) is an akinetic-rigid syndrome of unknown aetiology which…
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