Localization of basal ganglia and thalamic damage in dyskinetic cerebral palsy
Objective: To quantitatively consolidate published reports of deep grey matter injury in cerebral palsy to determine the patterns of injury associated with dystonia and dyskinesias.…Association of amyotrophic lateral sclerosis with basal ganglia impairment
Objective: The aim of this study is to define extent of basal ganglia involvement in amyotrophic lateral sclerosis (ALS). Methods: The study included 45 patients…Deep brain stimulation of the locomotor mesencephalic region in rats with lesioned sensorimotor cortex: A model of functional motor recovery after stroke
Objective: To evaluate whether electrical stimulation of the locomotor mesencephalic region (LMR) in rats with lesioned sensorimotor cortex improves (1) locomotion assessed by the CatWalk…Loss of heart rate variability in ALS: Time and frequency domain assessment
Objective: The aim of this study was to investigate alterations in cardiac autonomic control during sleep in patients affected by ALS. Background: Amyotrophic lateral sclerosis…Relationship between balance, trunk impairment and hand function in Parkinson’s disease
Objective: Our aim is to examine the relationship between balance, trunk impairment and hand function in patients with PD. Background: Parkinson's disease (PD) is the…STRONG VOICE: Design of a multisite, open-label, longitudinal registry for patients with neurogenic dysphonia/dysphagia treated with vocal fold augmentation
Objective: To describe the benefits and risks of vocal fold augmentation treatment for patients with neurogenic dysphonia/dysphagia. Background: Neurogenic dysphonia/dysphagia represents laryngeal dysfunction, usually with…Neuroprotection effect of an endogenous amine, 1MeTIQ against disturbances in dopamine release induced by the neurotoxin, 6-OHDA: In vivo microdialysis study
Objective: The aim of the present study was to investigated using microdialysis methodology the impact of 1MeTIQ on the disturbances of in vivo dopamine release…A computational model of iron transport between the blood circulation and the brain
Objective: To create a mechanistic computational model of iron transport between the circulation and brain, permitting in silico investigation of homeostatic regulation of iron at…Dynamic prediction for multiple repeated measures and event time data: An application to Parkinson’s disease
Objective: To develop methods for model-based personalized dynamic prediction of future outcome measure trajectories and risks of target events for the Parkinson's disease patients. Background:…Duloxetine, a serotonin and norepinephrine reuptake inhibitor, reduces daily OFF time in Parkinson’s disease
Objective: To evaluate efficacy of duloxetine on motor symptoms in Parkinson's disease (PD) patients with wearing-off in an open label trial. Background: Duloxetine, a serotonin…
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