Individualized botulinum toxin type A therapy of bilateral upper limb essential tremor by multi-sensor kinematic technology
Objective: To demonstrate efficacious and safe reduction in bilateral upper limb tremor severity by serial botulinum toxin type A injection parameters kinematically determined using a…"Are patients with familial ET distinct from those with sporadic ET? Insight from 250 patients"
Objective: To explore if patients with familial ET(FET) are clinically and demographically distinct from those with sporadic ET(SET). Background: Essential tremor(ET) is the commonest tremor…Timing control of gait in essential tremor patients vs. age-matched controls
Objective: (1) To examine if gait timing control is impaired in ET patients compared with age-matched controls. (2) To examine whether timing impairments are related…Quantitative analysis of tremor in patients with cerebellar and brainstem lesions
Objective: The aim of our study was to investigate the characteristics of tremor in patients with cerebellar or brainstem lesions. Background: The cerebellum and the…Core set of measures of balance for people with multiple sclerosis and cerebellar ataxia
Objective: To examine the reliability, validity and interpretability of four measures in assessing the severity of balance dysfunction and short term treatment benefits on balance…Fragile X-associated tremor/ataxia syndrome in two female patients
Objective: To report two cases of female patients with FXTAS. Background: Fragile X-associated tremor/ataxia syndrome (FXTAS) is a neurodegenerative disorder with core features of action…A unique phenotype associated with anti-GAD antibodies
Objective: To describe a case of hemiatiaxia, parkinsonism, and dystonia associated with anti-Glutamic Acid Decarboxylase (GAD) antibodies. Background: GAD antibodies have been implicated in endocrinopathies…Phenotypic insights into ADCY5-associated disease
Objective: We provide detailed clinical data on seven patients from six new kindreds with mutations in the ADCY5 gene, in order to expand and define…Suicide attempts and Huntington’s disease: Perseveration, not just impulsivity
Objective: To present the hypothesis that perseveration, not just impulsivity, is a risk factor for suicide attempts in Huntington's disease (HD). Background: The elevated incidence…Structural connectivity networks in prodromal and clinical Huntington’s disease
Objective: To investigate how structural connectivity correlates with the number of CAG repeats, disease evolution and clinical measures in presymptomatic (preHD) and clinical Huntington Disease…
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