Electrophysiological activity of anatomically identified STN subterritories in Parkinson’s disease
Objective: To characterize the electrophysiological activity of the subthalamic nucleus (STN) functional subterritories, as anatomically defined on fused CT/MRI images or by the recording tract…Is the PPN a valuable target for deep brain stimulation in treatment of Parkinsonian disorders? Experience of a patient’s series
Objective: Deep brain stimulation (DBS) of the pedunculopontine nucleus (PPN) has been reported to improve motor symptoms in idiopathic (IPS) and in atypical Parkinsonian syndromes…Comparison of clinically derived and model based programming parameters of subthalamic nucleus stimulation in Parkinson’s disease
Objective: To test whether DBS parameters in chronically stimulated Parkinson´s disease (PD) patients chosen by clinical criteria are congruent with DBS parameters as derived from…Unilateral focused ultrasound thalamotomy in tremor-dominant Parkinson’s disease
Objective: To evaluate the safety, feasibility, and durability of focused ultrasound thalamotomy on tremor in PD. Background: Surgical treatment of PD currently involves deep brain…Finger tapping distance in idiopathic normal pressure hydrocephalus changes in parallel with frontal lobe function
Objective: We assessed upper extremity function of idiopathic normal pressure hydrocephalus (iNPH) patients by quantitative finger tapping test and checked the correlation with other clinical…Deep brain stimulation outcomes for dystonia in adult and pediatric patients at Gillette Children’s Specialty Healthcare
Objective: Gillette Children's Specialty Healthcare is a non-profit independent hospital whose aim is to provide care to medically complicated patients with a special focus on…Disease stage classification of the cerebellar variant of multiple system atrophy based on voxel-based morphometry
Objective: We previously reported that voxel-based morphometry (VBM) is effective for classifying the disease types causing cerebellar atrophy. In the present study, with the objective…Quantitative MRI measurement of regional cerebellar involvement in patients with progressive supranuclear palsy
Objective: We aimed to evaluate cerebellar involvement in PSP using MRI segmental volumetric analysis. Background: Progressive supranuclear palsy (PSP) is characterized clinically as postural instability…Impaired hippocampal neurogenesis associates with serotonergic axonal degeneration in transgenic rat and mouse models of Parkinson’s disease
Objective: To evaluate the impact of α-synuclein accumulation on the hippocampal serotonergic system and hippocampal plasticity in two different α-synuclein expressing rodent models. Background: Parkinson's…Vitamin D in early Parkinson’s disease
Objective: To determine serum 25-hydroxy vitamin D (25OHD) concentration at diagnosis and 18 months in incident Parkinson's disease (PD) compared to controls and to investigate…
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