Direct assessment of psychosocial measures using eye tracking technology in advanced ALS – Can preserved autonomy and psychological wellbeing modify disease course?
Objective: To assess psychosocial functioning in advanced ALS in a fully independent manner. Background: ALS is a fatal motor neuron disease, with progressive paralysis, dysarthria,…Broadening the evaluative scope of quality of life in Parkinson’s: Testing the construct validity of the ICECAP-O instrument
Objective: To test the construct validity of ICECAP-O in Parkinson's and explore its relationship with the EQ-5D and the PDQ-39. Background: Parkinson's significantly affects patients'…Caring for the majority: Telemedicine management of Parkinson’s disease (PD) in underserved populations in People’s Republic of China: A randomized trial
Objective: To improve PD care using expert telemedicine consultation to assist community neurologists in managing PD. Background: Half of the world's PD patients live in…Implementation of a mobile application in the Luxembourg Parkinson’s study for identification and validation of disease stage and variation
Objective: The project focuses on integrating a mobile application (mPower) into the Luxembourg Parkinson's cohort (HELP-PD) to monitor frequency and degree of variation in symptoms…Development of the UK hereditary spastic paraplegia registry: Analysis of SPAST patients reveals high rate of psychiatric comorbidities
Objective: To (1) describe the genetic variability, phenotype and epidemiology of spastin mutation in HSP patients (2) create the UK HSP register with a focus…Genetic analysis of eighty-seven multiple system atrophy patients
Objective: To analyze candidate genes in a cohort of 87 patients with a clinical diagnosis of probable MSA. Background: Multiple System Atrophy (MSA) is a…Response to thermal and pain stimulation and genetic variance for pain in patients with Parkinson’s disease – Are they all related?
Objective: To examine whether there is a connection between clinical findings, genetics and QST data of Parkinson's disease(PD) patients and to characterize the genetic mechanisms…Hereditary atypical parkinsonism with novel mutation of the VPS35 and FBXO7 genes
Objective: To determine the genetic background of hereditary atypical parkinsonism in an isolated region of the Czech Republic. Background: A higher prevalence of parkinsonism was…C9ORF72 intermediate repeat copies as a rare genetic cause of atypical Parkinsonian syndromes or Parkinson’s disease complicated by psychosis in a Sardinian population
Objective: To screen for the presence of C9ORF72 repeat expansions in patients affected by atypical parkinsonism syndromes and PD complicated by psychosis or dementia, and…Coding and non-coding glucocerebrosidase variants have an impact on cognitive decline in Parkinson’s disease
Objective: To evaluate the impact of genetic variants in the Glucocerebrosidase gene (GBA) on cognitive impairment in a large cohort of Parkinson's disease (PD) patients…
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