Objective: This study aims to translate the Wearing-Off Questionnaire (WOQ) 19 into Filipino (F-WOQ-19) and validate the translated questionnaire.

Background: Parkinson’s disease (PD) is a common neurodegenerative disorder with Levodopa (LD) as the most effective for symptomatic treatment. The use of LD, however is associated with the development of motor complications such as wearing-off (WO) phenomenon and dyskinesias.

Methods: This study is a validation study. The WOQ-19 questionnaire was translated to Filipino (F-WOQ-19) using the forward and backward translation. Patients diagnosed with idiopathic PD who fulfilled the inclusion criteria were included in the study.   Recruited patients were asked to answer the F-WOQ-19. Afterwards, the authors interviewed the patients and assessed them using the Unified Parkinson Disease Rating Scale and  Wearing-Off Questionnaire-32 (WOQ-32). Data analysis was done using Stata SE version 13. The demographics and disease-related characteristics were tabulated. Consistency of the questions was measured using Cronbach’s alpha and paired-t-test. Criterion-related validity was measured by obtaining the correlation between WOQ-32 and F-WOQ-19 was analyzed using Pearson’s Product-Moment Correlation.

Results: The age of the participants (n=46) ranged from 40 to 86 years old. 56% of the participants were male. Majority of the patients (34.78%) have a H&Y staging of 2. A total of 40 patients claimed that they have WO. The internal consistency of the F-WOQ-19 as measured by Cronbach’s alpha is acceptable at 0.7808 and the paired t-test showed no significant difference (p=0.291) in F-WOQ-19 scores on follow-up.  The correlation of the validated WOQ-32 and the F-WOQ-19 is high at 0.8191. The troublesome symptoms for patients were tremor, insomnia, weakness and slowness. It is essential to emphasize that one of these is a non-motor symptom.

Conclusions: The high correlation and acceptable internal consistency reinforces the eligibility of the F-WOQ-19 to be administered to Filipino PD patients.

*Submitted the abstract at the 2017 3rd Taiwan International Congress of Parkinson’s Disease and Movement Disorders to be held on March 17-19, 2017 in Taipei, Taiwan

The result is yet to be released by January 9, 2017. 

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MDS Abstracts - https://www.mdsabstracts.org/abstract/translation-and-validation-of-the-filipino-version-of-the-wearing-off-questionnaire-19-f-woq-19/