Objective: Objective of the study was investigating th neurological, neurochemical, neuroimaging and psychological features of children (5 to 15 years) with chronic tic disorder.

Background: In the general population the prevalence of ticks is quite large and the statistics of different countries is 1 – 13%. There are two main theories of ticks: genetic determination and neurogenic stress on the background of residual-organic lesions of various structures of the extra pyramidal system.

Methods: We performed a neurological, neurochemical (determination of catecholamines in the urine), neuroimaging (MRI) and psychological examination of children (5 to 15 years) with chronic tic disorder. total number of 250 children were studied.

Results: On the basis of complex neuropsychiatric examination, changes of catecholamines; neuroimaging and follow-up of children with chronic tic disorder evaluated the efficacy of the treatment of chronic tic disorder in children and indications for drug therapy, developed criteria for early diagnostics of ticks in the debut of hereditary degenerative diseases.

Conclusions: We did set multifactor genesis of chronic tic disorder, resulting from organic brain damage in childhood and psychological characteristics of the child’s personality and its interaction with other people. At follow-up study we found that chronic tic disorder may be the initial manifestation of progressive diseases of the nervous system. The features of emotional-personal sphere of children with chronic tics and features of the interaction of the child with chronic tics within the family were identified. Thus, the primary tics can be considered typical of neuropsychiatric disorders. In MRI study any specific for chronic tic disorder changes were not found.

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MDS Abstracts - https://www.mdsabstracts.org/abstract/tick-disorders-in-children-and-differential-diagnosis-with-progressive-diseases-of-the-nervous-system/