Objective: To promote and facilitate learning by providing resources and expertise to address the training needs of the Global Parkinson’s Genetics Program (GP2; www.gp2.org) and its collaborators.

Background: GP2 is an international collaborative effort committed to advancing our understanding of the genetic basis of Parkinson’s disease (PD). Alongside building strong connections with global partners, training the next generation of PD researchers worldwide is a key priority for GP2.

Method: The Training and Networking group has strategically developed resources and training opportunities to achieve global impact. We have developed a free online web-based learning platform (https://training.gp2.org/) dedicated to establishing foundational knowledge in PD genetics, data science and bioinformatics. Tailored training opportunities have been provided to clinicians and scientists from traditionally underrepresented regions in PD research to equip them with research skills and build local capacity.

Results: Eight courses have been launched on the GP2 Learning Platform thus far; accessed by 800+ trainees. A course on whole-genome sequencing data analysis is in development. A Visiting Scientist Program has been created to support established scientists to pursue new avenues of research aligned to our mission. To address gaps in clinical research opportunities in underrepresented regions, we launched regional training initiatives. The first, held in Kyrgyzstan, included a 3-day workshop and webinars throughout 2024. A Trainee Network of 225+ members worldwide is guided by a team of regional trainee representatives, who have streamlined training, knowledge exchange, and collaborative data analysis across GP2. Three in-person bioinformatics training workshops in Colombia, Mexico and India, along with a hybrid Hackathon, involving trainees from 20+ countries have further enriched the training experience. 11 PhD and 12 master’s fellowships have been awarded to individuals in Africa, Asia, Australia and Latin America. Sabbatical opportunities at GP2 centers have been extended to Trainee Network members.

Conclusion: As GP2 continues to grow, we are working to ensure local research capacity is developed and to support the expanding network of trainees and researchers worldwide. These efforts contribute significantly to advancing our understanding of the genetic basis of PD.

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MDS Abstracts - https://www.mdsabstracts.org/abstract/strategic-training-framework-for-advancing-research-capacity-through-gp2/