Category: Parkinson's Disease: Non-Motor Symptoms
Objective: We quantitatively evaluated skin condition of patients with autonomic dysfunction.
Background: Dyshidrosis are known to be one of autonomic symptom in Lewy body disease (LBD). Seborrheic face is one of the most common features in Parkinson disease and is often experienced in clinical practice.
Method: Twenty-six patients (13 males and 13 females) with autonomic failure who attended our clinic were included in the study. The 26 patients included 16 patients with LBD, 4 patients with multiple system atrophy, and 6 patients with other disorders. The 26 patients included 16 patients with LBD, 4 patients with multiple system atrophy, and 6 patients with other diseases. All patients were evaluated in the untreated condition without any medication such as Levodopa. Oil, moisture, and pH were measured in the forehead, posterior neck, thorax, abdomen, and extremities of the patients while they were lying in bed, and their trends were compared. Pearson’s correlation coefficient and Wilcoxon rank-sum test were used for testing.
Results: Negative correlations between oil and moisture were observed only in the forehead area (r=0.546, p=0.007). No correlation was found in the posterior neck, thorax and abdomen, and extremities. The LBD group tended to have higher oil content in the forehead area than the non-LBD group (mean: 128.2/87.7; p=0.17), although there was no significant difference between the LBD and non-LBD groups. The non-LBD group was divided into two groups, MSA and non-MSA, and the results showed that the non-MSA group tended to have lower oil content in the forehead area (mean: 128.2/102.8/77.7).
Conclusion: The results quantitatively showed that impaired sweating increased the oil content of the skin. The results suggest that seborrheic facial features may be more likely to appear in patients with LBD than in those with suspected autonomic neuropathy. The number of cases is small, and further accumulation of cases is needed.
To cite this abstract in AMA style:
R. Sengoku, A. Nakahara, T. Kitagawa, M. Ikeda, H. Matsuno. Quantitative Evaluation of Seborrheic Dermatitis in Patients with Autonomic Dysfunction. [abstract]. Mov Disord. 2023; 38 (suppl 1). https://www.mdsabstracts.org/abstract/quantitative-evaluation-of-seborrheic-dermatitis-in-patients-with-autonomic-dysfunction/. Accessed May 13, 2025.« Back to 2023 International Congress
MDS Abstracts - https://www.mdsabstracts.org/abstract/quantitative-evaluation-of-seborrheic-dermatitis-in-patients-with-autonomic-dysfunction/