Objective: To study epidemiological condition of Parkinson disease in the world.

Background: Parkinson’s disease (PD) is a long-term degenerative disorder  of the central nervous system that mainly affects the motor system. The cause   of Parkinson’s disease is generally unknown, but believed to involve both genetic and environmental factors. Those with a family member affected are more likely to get the disease themselves. Diagnosis of typical cases is mainly based on symptoms, with tests such as neuroimaging being used to rule out other diseases. Nowadays PD affected 6.2 million people and resulted in about 117,400 deaths globally. Parkinson’s disease typically occurs in people over the age of 60, of which about one percent are affected. Males are more often affected than females at a ratio of around 3:2. When it is seen in people before the age of 50, it is called early-onset PD. The average life expectancy following diagnosis is between 7 and 14 years.

Method: Major epidemiological and statistical articles published during the past 10 years which dedicated to stroke were reviewed.

Results: In many developed countries the incidence of stroke is declining even though the actual number of Parkinson disease is increasing because of the ageing population. It means  that pathology is age-dependent. So, with a total prevalence of PD in the range of 150-300 per 100 thousand. Population incidence increases significantly in older age groups. In the group over 65 years there has been 1700 cases per 100 thousand population (Walters EC, 2007). It is estimated that every tenth patient PD begins before 50 years, every twentieth – up to 40 years.  In connection with this release a special subgroup – PD with early onset at age debut in the range of 21 to 40 years. The term “youthful (juvenile)” Parkinson’s is used when symptoms appear up to 20 years.

Conclusion: The “perfect” Parkinson disease incidence study does not exist. There is a need for further studies to fill the gaps in our knowledge of the worldwide incidence of Parkinson disease, particularly for developing countries. It is very difficult to get the accurate numbers this diseases dissemination due to unavailability of a single registry as well as the fact that Parkinson disease is often intentionally or mistakenly not diagnosed or passes under the different diagnoses (stroke), which are not taken into the overall statistics of Parkinson disease.

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MDS Abstracts - https://www.mdsabstracts.org/abstract/prevalence-of-parkinsonian-syndrom-in-the-world/