Objective: This study was design to determine patient’s self-assessed health quality of life measures and mood. We also aimed at establishing the relationship between the health related quality of life and their demographic and clinical characteristics.

Background: Parkinson’s disease (PD) is a chronic neurodegerative disease that is characterized by motor and non-motor symptoms. It affects an estimated 4 million people worldwide. PD is associated with negative quality of life and mood disturbance that can affect the outcome of management.

Methods: Forty-nine consecutive consenting patients who presented at a Neurology clinic were evaluated using the Parkinson’s Disease Quality of Life Questionnaire (PDQ-39), the motor section of the Unified Parkinson’s Disease Rating Scale (UPDRS) and the Hospital Anxiety and Depression scale (HADS).

Results: The mean age of the patients was 61.27 years and the mean age at onset of symptoms was 57.65 years. They were made up of 73.5% males and 26.5 % females. The proportion with borderline anxiety, anxiety, borderline depression and depression were 8.2%, 4.1%, 22.4% and 4.1% respectively. Over 95% of the patients were above 40% on the Schwab and England activity of daily living scale, while over 60% of the patients were in stage 1 to 2.5 of the modified Hoehn and Yahr scale. The mean percentage scores for the elements of the PDQ39 among our patients were as follows: Mobility (MOB), 39.42%; Activities of Daily Living (ADL), 34.24%; Emotional wellbeing (EWB), 31.76%; Stigma (SG), 30.55%; Social Support (SS), 3.80%; Cognitive Impairment (CI), 22.71%; Communication (COM), 22.50% and Bodily Discomfort (BD) 32.18%. The PD summary Index (PDQ-I) for the group was 27.16%. We observed a significant correlation between anxiety scores on HADS with ADL, SS and BD (P value = 0.005, 0.016 and 0.045 respectively). For depression, significant correlation was observed for MOB and COM (P value = 0.041 and 0.003 respectively).

Conclusions: The prevalence of depression and anxiety was low among our cohort of PD patients. They had significantly high level of social support that contributed to a good quality of life reported by the patients.

« Back to 2018 International Congress

MDS Abstracts - https://www.mdsabstracts.org/abstract/prevalence-and-predictors-of-mood-and-health-related-quality-of-life-impairment-among-patients-with-parkinsons-in-sub-saharan-neurology-clinic/