Objective: To study clinical manifestations of Parkinson’s disease (PD) on the background of essential tremor (ET) in persons of Uzbek nationality.

Background: Parkinson’s disease often develops amid a significant tremor.

Methods: 34 patients with PD who developed against ET and 32 patients without ET were examined. Patients were aged 30 to 62 years (mean age 46.7± 8.1 years), of which 35 men and 31 women. All patients underwent clinical and neurological examinations.

Results: The obtained results show that the clinical manifestations of PD on the background of ET differs without ET. The duration of PD in the general group was 5.45±4.3 years. The longest duration was observed in patients of the first group (6.19±8.31 years), which developed against the background of ET. The first group of patients was more common in men (70.5%). Our observations show that not all cases of ET are transformed into PD, in 26.5% of patients there was no PD. Almost all patients with PD with ET were followed by a trembling-rigid form (82.3%). In the course of the first group, the patients differed from the second group, which had a progressive course.

Conclusions: Above described it should be noted that the clinic and the course of Parkinson’s disease against the background of ET has its own characteristics and depends on the sex, duration and form of the disease. ET is the main preclinical factor of PD development, which requires timely diagnosis and treatment.

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MDS Abstracts - https://www.mdsabstracts.org/abstract/parkinsons-disease-against-the-background-of-an-essential-tremor-in-people-of-uzbek-nationality/