Exome-wide and Mitogenome Sequencing of Indian Dystonia Patients
Objective: To identify whole exome and mitochondrial genome mutation spectrum of dystonia in India and to establish clinical significance of mutations by phenotype-genotype correlation. Background:…Dysconnectivity of the Parafascicular Nucleus in Parkinson’s Disease
Objective: The present study aimed to investigate the functional alterations of the parafascicular nucleus (Pf) projections in Parkinson’s disease (PD) patients. Background: Recent animal model…UMSARS versus laryngoscopy-based assessment of dysphagia
Objective: To compare the Unified Multiple System Atrophy Rating Scale (UMSARS) part I-item 2 with an ear/nose/throat (ENT) expert physician assessment. Background: Early and severe…Hemiparkinsonism secondary to a cerebral cavernous malformation (CCM)
Objective: To describe a case of secondary parkinsonism of unhabitual cause and complex treatment. Background: Secondary parkinsonism constitutes approximately 15% of all parkinsonism cases in…Decreased occurrence of dyskinesia when combining amantadine to L-DOPA in early Parkinson disease (PD): the PREMANDYSK trial
Objective: To assess amantadine effects on dyskinesia and other PD symptoms when adjunct to L-DOPA in early PD. Background: Amantadine is efficacious on L-DOPA-induced dyskinesia…Moving beyond trial and error: a strategy for anatomically informed contact selection in subthalamic deep brain stimulation for Parkinson’s disease.
Objective: In this study we aimed to investigate and compare the utility of conventional DBS programming strategies and anatomically informed approaches predicting long term motor…Exercise based priming and virtual reality for optimizing neuroplasticity and balance in Parkinson’s disease.
Objective: To determine the neurophysiological and behavioral effects of exercise-based priming and virtual reality in individuals with PD. Background: Individuals with Parkinson’s disease (PD) are…Prodromal dementia with Lewy bodies in REM sleep behavior disorder: A multicenter study
Objective: To assess the progression and predictive value of neuropsychological testing on the development of dementia in idiopathic REM sleep behavior disorder (iRBD). Background: iRBD…IP-RT-QuIC Identify Disease-Specific Alpha-Synuclein Seeds in serum from patients with syncleinopathy
Objective: To examine whether alpha-synuclein (aSyn) seed exists in the serum and its potential as a serum biomarker. Background: Parkinson’s disease (PD) and Multiple system…Diffusion imaging study of mild behavioral impairment in Parkinson’s disease.
Objective: Patients with Parkinson’s disease (PD) experience changes in behavior, personality, and cognition. Mild Behavioral Impairment (MBI) is a validated neurobehavioral syndrome that identifies a…
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