Polyaromatic hydrocarbons in Ambient Particulate Matter (PM 2.5) mediate neurodegeneration through the olfactory-brain axis in C57BL/6 mice
Objective: To delineate the molecular mechanisms involved in bidirectional olfactory-brain-induced neurodegeneration caused by exposure to ambient particulate matter (PM2.5). Background: Air pollution has been linked…Effects of an online 12-week Tai Chi intervention on gait and postural stability in individuals with Parkinson’s disease
Objective: To examine the effects of an online 12-week biomechanical-based TC intervention on gait and posture in people with Parkinson's disease (PD). Background: Postural instability…A novel motor-learning based dysphagia treatment approach in Parkinson’s disease
Objective: This pilot study tested the effectiveness of a novel motor learning and exercise principle-based dysphagia treatment approach in PD. Background: Dysphagia occurs in 90% percent…A juvenile onset Sandhoff disease case caused by hemizygous mutations of HEXB
Objective: Sandhoff disease (SD) is a rare neurological disease with high clinical heterogeneity. SD in juvenile form is much rarer and it is often misdiagnosed…Severe parkinsonism late-onset in Wilson’s disease without typical basal ganglia involvement
Objective: Wilson's disease (WD) is an autosomal-recessive copper metabolism disease caused by ATP7B mutations. Background: Here we described an interesting case of WD. Method: A…Systemic and intracellular iron starvation response in Friedreich´s Ataxia
Objective: To investigate the hepcidin-ferroportin mediated iron metabolism regulation in Friedreich´s Ataxia (FA). Background: FA is a devastating neurogenetic disorder caused by biallelic GAA expansions…Age-associated changes in the striatal proteins in aging Asian-Indians
Objective: To examine the age-related changes in tyrosine hydroxylase (TH), vesicular monoamine transporter2 (VMAT2), post-synaptic density protein-95 (PSD-95) and dopamine receptors (D1R, D2R) expression in the…blepharoplasty yes or not? a single-centre study on the influence of blepharoplasty on the treatment with botulinum toxin injections.
Objective: To compare the responses to the BoNT injections of patients who underwent or not to blepharoplasty (Blepharoplasty YES/NO), in order to clarify if the…Neurologic dysfunction assessment in Parkinson’s disease based on fundus photographs using deep learning
Objective: To develop an algorithm that can predict Hoehn and Yahr (H–Y) and Unified Parkinson's Disease Rating Scale part III (UPDRS-III) scores using fundus photography among…Persistence, Health Care Resource Utilization, and Costs Among OnabotulinumtoxinA-Treated Patients with Cervical Dystonia in the US
Objective: To compare health care resource utilization (HCRU) and costs among patients with cervical dystonia (CD) in the US who are persistent vs nonpersistent with…
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