Identification of reproducible metabolites for Parkinson’s Disease diagnosis using clinical data and computational modelling
Objective: To identify replicated metabolic markers of Parkinson’s Disease (PD) diagnosis from metabolomic studies and predict additional metabolic markers using computational metabolic modelling. Background: Reported metabolic markers of…Make-up for Parkinson’s: a randomized control trial
Objective: To assess the effectiveness of using “applying make-up" as a physiotherapy and occupational therapy intervention to reduce bradykinesia in people with Parkinson’s. Background: People…Effects of exergaming-based tai chi and eye movement training on balance and gait in progressive supranuclear palsy: a case report
Objective: To evaluate the effectiveness of exergaming-based tai chi and eye movement training in improving functional balance, gait and quality of life in a patient…Custom-made Application Interface using Wacom® Tablet for Assessment of Writer’s Cramp
Objective: To evaluate a custom designed software platform to digitise handwriting data in writers cramp and normal controls. Background: Focal task specific dystonia occurring while…Cervical dystonia with early onset as initial manifestation of adult-onset Huntington’s disease
Objective: To describe a rare case of adult-onset HD that presented with early-onset cervical dystonia as the only and prominent symptom. Background: Except for chorea,…Evaluation of neuroprotective role of carvacrol via Nrf2-NLRP3 axis in rotenone induced PD mice model
Objective: To explore the antioxidant and anti-inflammatory role of Carvacrol via Nrf2-NLRP3 axis in rotenone induced PD mice model Background: NLRP3 inflammasome mediated neuroinflammation is…Prevalence of cardiovascular drugs and oral anticoagulants use among persons with and without Parkinson’s disease
Objective: We investigated prevalence of Cardiovascular drugs and Oral anticoagulants (OAC) use among community-dwelling persons with and without Parkinson's disease (PD) in relation to PD…Effect of ADX-88178, a highly-selective mGlu4 PAM, on parkinsonism, dyskinesia and psychosis-like behaviours in the MPTP-lesioned marmoset
Objective: To investigate the effect of the metabotropic glutamate 4 (mGlu4) positive allosteric modulator (PAM) ADX-88178 on parkinsonism, dyskinesia and psychosis-like behaviours (PLBs) in the…Selenium mitigates ferroptosis-mediated dopaminergic cell death by regulating the Nrf2/GPX4 pathway: Implication for Parkinson’s disease
Objective: The objective of this study is to explore the protective properties of selenium in an in vitro PD model, especially focusing on its underlying…Experiences of People with Parkinson’s Disease use of a wearable technology for the management of drooling; qualitative insights from the Cue Band study
Objective: In the Cue Band study, people with Parkinson’s Disease (PwP) are participating in a randomised controlled trial to compare a mobile Application (App) with…
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