Patient characteristics and real-world use of botulinum toxins for treatment of cervical dystonia and blepharospasm
Objective: To describe the characteristics of patients with cervical dystonia (CD) or blepharospasm (BLEPH) treated with botulinum toxin (BoNT) in routine care using claims data…Effect of ADX-88178, a highly-selective mGlu4 PAM, on parkinsonism, dyskinesia and psychosis-like behaviours in the MPTP-lesioned marmoset
Objective: To investigate the effect of the metabotropic glutamate 4 (mGlu4) positive allosteric modulator (PAM) ADX-88178 on parkinsonism, dyskinesia and psychosis-like behaviours (PLBs) in the…Selenium mitigates ferroptosis-mediated dopaminergic cell death by regulating the Nrf2/GPX4 pathway: Implication for Parkinson’s disease
Objective: The objective of this study is to explore the protective properties of selenium in an in vitro PD model, especially focusing on its underlying…Empowerment of People with Parkinson`s disease: development, testing and evaluation of a cross-sectoral, intervention-based self-management program
Objective: The overall purpose of this study is to develop, test and evaluate the results of a self-management program targeted PwP with the aim of…Long term effects of Deep Brain Stimulation on Camptocormia in Parkinson’s disease
Objective: Camptocormia (CC) as a syndrome often is a major burden for patients with Parkinson’s Disease (PD). In the absence of response to levodopa (except…Signs of Respiratory Dysfunction across Parkinson’s Disease Spectrum
Objective: The aim of the study is to investigate signs of respiratory dysfunction across the Parkinson’s disease spectrum. Background: Respiratory dysfunction in Parkinson’s disease (PD)…Visual dysfunction of the Superior Colliculus in idiopathic Blepharospasm: a pilot study
Objective: To investigate the role of the superior colliculus (SC) using functional brain MRI (fMRI) and a visual stimulation paradigm based on luminance contrast variations…Diffuse cerebellar edema in acute anti-Yo positive paraneoplastic cerebellar degeneration: A case report
Objective: To report a case of acute anti-Yo positive paraneoplastic cerebellar degeneration (PCD) with atypical brain MRI findings. Background: PCD is a rare disease but…Polyaromatic hydrocarbons in Ambient Particulate Matter (PM 2.5) mediate neurodegeneration through the olfactory-brain axis in C57BL/6 mice
Objective: To delineate the molecular mechanisms involved in bidirectional olfactory-brain-induced neurodegeneration caused by exposure to ambient particulate matter (PM2.5). Background: Air pollution has been linked…Use of stimview technology in deep brain stimulation of Parkinson´s disease patients
Objective: We present our experience of Stimview technology in the neurostimulation of 5 patients with Parkinson´s disease (PD). Background: It is common to make adjustments…
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