Transcriptomic profiling in DYT1 dystonia: unravelling pathogenic pathways.
Objective: The aim of this project is to investigate post-mortem brain tissues, iPSC and iPSC-derived neurons from controls and patients with DYT1 dystonia to find…May CSF biomarkers have a role in degenerative parkinsonian syndromes workup?
Objective: To evaluate the role of cerebrospinal fluid (CSF) biomarkers in the differential diagnosis of degenerative parkinsonian syndromes. Background: The differential diagnosis of degenerative parkinsonian…Advanced programming strategies in subthalamic DBS: Just a gimmick or well-established in clinical routine?
Objective: To evaluate the application of commonly available advanced programming strategies in deep brain stimulation (DBS) of the subthalamic nucleus (STN) in patients with Parkinson’s…Understanding Parkinson’s Disease Patients’ and Carepartners’ Palliative Care Knowledge & Preferences
Objective: To describe the knowledge and preferences of people with Parkinson’s (PWP) and care partners (CP) related to outpatient palliative care (PC). Background: PWP and…Randomized, waitlist-controlled trial of Karate Intervention to Change Kinematic Outcomes in PD (KICK OUT PD)
Objective: To test the adherence to and efficacy of twice-weekly karate classes for people with mild to moderate Parkinson’s Disease (PD) on quality of life…A Comparison of Cervical Dystonia in Parkinson’s Disease and Idiopathic Isolated Cervical Dystonia
Objective: To perform a prospective analysis of the prevalence and clinical characteristics of cervical dystonia in Parkinson’s disease (CD-PD) and compare these features to those…Signs of Respiratory Dysfunction across Parkinson’s Disease Spectrum
Objective: The aim of the study is to investigate signs of respiratory dysfunction across the Parkinson’s disease spectrum. Background: Respiratory dysfunction in Parkinson’s disease (PD)…Sub-cellular alterations in MPTP-induced in-vivo and in-vitro systems and Non-MPTP human Parkinsonian skin biopsies: Verifying the sequelae of differential toxicity
Objective: To evaluate the possible temporal hierarchy of sub-cellular organellar degeneration in experimental models of Parkinson’s disease (PD), using MPTP/MPP+ Background: Higher prevalence of PD in…D-penicillamine induced myasthenia gravis – the possible complication of Wilson’s disease treatment.
Objective: D-penicillamine (DPA) belongs to the most frequently used drugs in Wilson’s disease (WD) treatment. Despite the effectiveness in WD treatment, DPA could be involved in many…Gene-environment interactions for Parkinson’s disease
Objective: The aim of this study was to test for interactions between PD-related genetic and phenotypic traits in the 23andMe, Inc. research cohort. Background: Parkinson’s…
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