Multicenter, randomized, placebo-controlled, double-blind, parallel-group proof-of-concept study of lixisenatide in patients with early Parkinson’s disease (PD): the LIXIPARK trial (NCT03439943)
Objective: To evaluate the “disease-modifying” effect of lixisenatide as adjunct to antiparkinsonian medications in patients with early PD. Background: Lixisenatide, a glucagon-like peptide 1 receptor…Longitudinal change in clinical characteristics of LRRK2 carriers in a remote cohort
Objective: To examine change in clinical characteristics in LRRK2 G2019S carriers with Parkinson’s disease (PD) and without PD (non-manifest carriers) enrolled in Virtual Assessment of…Development and preliminary results of a new picture-based self-rating tool for neuropsychiatric syndromes in Parkinson’s disease
Objective: To develop a picture-based, non-verbal screening tool to detect neuropsychiatric syndromes (NPS), including depression, anxiety, apathy, fatigue, mania, impulse control disorder (ICD), sleeping problems,…Functional movement disorders in dopa-responsive dystonia – A case series with implications for diagnosis and treatment
Objective: A detailed clinical characterization of functional movement disorders (FMD) in dopa-responsive dystonia (DRD) patients. Background: FMD are one of the most common conditions in…Quantifying the value of multimodal MRI in outcomes prediction for STN DBS in PD
Objective: To compare the predictive value for motor outcomes of multimodal MRI to clinical predictors alone in STN DBS for PD. Background: STN DBS is…Dysconnectivity Profiles of Raphe Nuclei in Parkinson’s Disease: From Prodromal to Advanced Stage
Objective: To investigate the functional connectivity changes of dorsal raphe (DR) and median raphe (MR) nucleus in patients with PD from the prodromal to advanced…Post stroke Restless Limb Syndrome and its impact on sleep and life quality in patients in Rural Gujarat, India
Objective: We aimed to assess the prevalence of RLS in patients with brain stroke and assess its impact on sleep and quality of life. We…Peroperative use of the MDS-UPDRS Motor Section: Agreement between Sitting and Supine position
Objective: To assess the level of agreement between the MDS-UPDRS-III in sitting and supine position. Background: The clinical effect during stereotactic neurosurgery for Parkinson’s disease…Incidence of dysphagia and comorbidities in patients with cervical dystonia, analyzed by botulinum neurotoxin treatment exposure
Objective: Describe real-world incidence of dysphagia and other comorbidities in adults with cervical dystonia (CD) treated and not treated with botulinum neurotoxin (BoNT). Background: Dysphagia…Exome-wide and Mitogenome Sequencing of Indian Dystonia Patients
Objective: To identify whole exome and mitochondrial genome mutation spectrum of dystonia in India and to establish clinical significance of mutations by phenotype-genotype correlation. Background:…
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