The efficacy of Botulinum toxin A in reducing muscle spasticity by different volumes of dilution
Objective: Spasticity is a speed-dependent increase in muscle tone associated with stiffness, enhanced osteotendinous reflexes, paresis, loss of fine motor control, and increased fatigue. The…GAIT ANALYSIS IN PARKINSONIAN SUBJECTS WITH PISA SYNDROME SUBJECTED TO TREATMENT WITH BOTULINUM TOXIN
Objective: The aim was to evaluate the activation characteristics of the muscles involved in patients with Pisa Syndrome with surface electromyography (EMG) during walking after…Action verb use in PD: A challenge to the embodied cognition hypothesis?
Objective: To characterize action verb production in Parkinson's disease (PD) during a picture description task, and evaluate associations with motor and cognitive function. Background: The…Alien hand syndrome in ischemic stroke: a case-report
Objective: Alien hand syndrome (AHS) is a rare movement disorder that inspires fear to patients and confuses doctors. So we describe a rare case-report. Background:…A randomized controlled trial comparing the efficacy and safety of pyridostigmine versus midodrine for the treatment of orthostatic hypotension in Parkinson’s disease patients
Objective: To assess the long-term efficacy and safety of pyridostigmine and midodrine in the treatment of OH in PD. Background: In Parkinson's disease (PD), orthostatic…Blaming neuromelanin for Parkinson’s disease: time-dependent tyrosinase overexpression drives endogenous synucleinopathy in non-human primates
Objective: Development and characterization of a novel non-human primate model of Parkinson’s disease based on the AAV-mediated forced expression of human tyrosinase Background: Although neuromelanin…Use of apomorphine infusion pump in the elderly population : a 5 years follw up study on efficacy, safety and tolerability in a cohort bases study
Objective: Evaluate the efficacy, tolerability and safety of subcutaneous apomorphine infusion in elderly patients with advanced Parkinson's disease in a five years follow up cohort. Background: Continuous infusion by subcutaneous apomorphine pump has…Imaging Tau in Atypical Parkinsonisms: Meta-Analysis of in vivo PET Imaging Findings
Objective: To determine the most accurate and reliable tau PET tracers for providing differential diagnosis of PSP and CBD from PD. Background: Parkinsonism is classified…Subcutaneous Foslevodopa/Foscarbidopa in Patients With Advanced Parkinson’s Disease: Results From a Randomized, Double-blind, Double-dummy Phase 3 Trial
Objective: To evaluate the efficacy and safety/tolerability of 24-hour/day continuous subcutaneous infusion (CSCI) of foslevodopa/foscarbidopa (a soluble formulation of levodopa/carbidopa prodrugs) vs oral levodopa/carbidopa in…Dopaminergic Denervation as Predictors of Axial Dysfunction in Parkinson’s Disease
Objective: We aimed to assess the usefulness of dopamine binding scores as predictors of walking and balance problems and freezing of gait (FoG) in PD.…
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