Effect of KW-6356, a novel adenosine A2A receptor antagonist/inverse agonist, on motor and non-motor symptoms in Parkinson’s disease patients as an adjunct to levodopa therapy: Results of Phase 2b study
Objective: To evaluate the efficacy and safety of KW-6356 in Parkinson’s disease (PD) patients with levodopa therapy, irrespective of the presence of wearing-off (WO). Background:…Double trouble: Association of malignant melanoma with sporadic and genetic forms of Parkinson’s disease and asymptomatic carriers of related genes in the PPMI study.
Objective: The aim of the present study was to assess the prevalence of malignant melanoma (MM) in sporadic and genetic Parkinson’s disease (PD) patients and…Impact of ApoE genotype on cognition in idiopathic and genetic forms of Parkinson’s disease
Objective: The aim of our current report was to assess the impact of Apolipoprotein-E (ApoE) genotype on cognition in idiopathic Parkinson’s disease (PD) patients and…Juvenile Huntington’s Disease in Tunisia: Clinical Diversity and Literature review
Objective: We conducted the first JHD clinical and molecular features in Tunisia and North Africa, contributing to better understanding the diverse manifestation of the disease…Characterization of routine botulinum toxin (BoNT) therapy and patient population in cervical dystonia
Objective: We conducted a survey to characterize real-world treatment of CD patients with focus on treatment duration, clinical parameters and awareness of clinical resistance as…Mimics or multiplicity: two patients with a PSP phenotype and underlying genetic neurodegenerative disorders.
Objective: To describe a two cases of patients presenting with a PSP phenotype and genetic findings consisted with Huntington’s disease (HD) in one case and…Three patients with PSP presenting with a logopenic pattern of aphasia: expanding the phenotype of language impairment in PSP.
Objective: To investigate the a series of cases presenting with apparent logopenic variant primary progressive aphasia who then developed symptoms suggestive of PSP. Background: Deficits…Cognitive and Motor aspects of a Brazilian population with Parkinson´s disease and Impulse Control Disorders and/or Related Behaviors – an observational study.
Objective: We analysed if Impulse Control Disorders (ICDs) and/or Related Behaviors (RBs) were associated with levodopa-induced dyskinesia (LIDs) in Brazilian patients with Parkinson´s disease (PD)…Impact of dopamine replacement therapies on MDS-UPDRS II
Objective: To estimate the longitudinal effect of different dopamine therapies on the Movement Disorder Society-Sponsored Unified Parkinson's Disease Rating Scale Part II (MDS-UPDRS II) among…Sarcopenia Screening with Limb Circumference and Impacts of Sarcopenia in Parkinson’s disease
Objective: In this study, we evaluated limb circumference as sarcopenia screening tool in PD and comprehensively investigated the impacts of sarcopenia in PD. Background: Sarcopenia…
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