IParkours : Role of the advanced practice nurse (APN) in the support/follow-up of parkinsonian patients.
Objective: Specify the contribution of APN in the follow up of patient (prescription, follow-up rate, health literacy).Expected evolution to increase the impact of the physician.Fluidify…Improved Tremor Response to Focused Ultrasound Thalamotomy
Objective: This study sought to determine if, when using four tract tractography (FTT) to target the decussating and non-decussating dentatorubrothalamic tracts (DRTTs), essential tremor (ET)…Early cortical atrophy is related to depression in Parkinson’s disease
Objective: To investigate depression in relation to medial temporal lobe atrophy (MTA), global cortical atrophy (GCA) and white matter hyperintensities (WMH) in neuropathologically confirmed patients…Ipilimumab/Nivolumab-related orthostatic myoclonus in a patient with metastatic melanoma
Objective: To describe a case of delayed onset Orthostatic Myoclonus in a patient after withdrawal of checkpoint inhibitor immunotherapy. Background: Movement disorders have been described…A tau-directed monoclonal antibody could alter the tau pathology of progressive supranuclear palsy
Objective: The purpose of this study is to examine the modification of tau pathology in brain regions of a patient with progressive supranuclear palsy (PSP)…Association between severity of freezing of gait and turning characteristics in Parkinson’s disease
Objective: To investigate the turning characteristics of people with Parkinson’s disease (PD) with freezing of gait (FoG) according to the turning direction. Background: For people…Leveraging MRI and machine-learning for early detection of cognitive impairment in Parkinson’s disease
Objective: To develop a machine learning model using MRI data that predicts the likelihood of cognitive impairment in newly diagnosed patients with Parkinson's disease (PD).…Neuromelanin related 7T MRI of the locus coeruleus differs between Parkinson’s disease and controls
Objective: To compare the signal intensity of the substantia nigra and locus coeruleus on Magnetization Transfer 7T MRI between PD patients and healthy controls (HC)…Determination of metabotropic glutamate 2 receptor distribution with [3H]-LY-341,495 in hemi-parkinsonian rats with L-DOPA-induced dyskinesia
Objective: To determine the distribution and density of metabotropic glutamate 2 (mGlu2) receptors in the motor loop of the basal ganglia in 6-hydroxydopamine (6-OHDA)-lesioned rats…Characterisation of the pharmacokinetic profile of L-DOPA in the common marmoset
Objective: To determine the pharmacokinetic (PK) profile of L-3,4-dihydroxyphenylalanine (L-DOPA) in the common marmoset (Callithrix jacchus). Background: The common marmoset has been used to model…
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