Machine learning algorithms for classification and analysis of pen-on-paper Archimedes spirals
Objective: To classify tremor syndromes from freely hand drawn pen-on-paper Archimedes spirals using classical machine learning techniques. Background: Spiral drawings (Archimedean) are commonly used in…CLINICAL AND GENEOLOGICAL FEATURES OF PARKINSON’S DISEASE
Objective: The initial purpose of the work is to study the clinical and genealogical features of Parkinson's disease. Background: Currently, clinical genetics has a number…Descriptive case studies of patients in their fifth consecutive year of treatment with ND0612
Objective: To describe the long-term experience of three individual patients receiving subcutaneous (SC) levodopa/carbidopa infusion with ND0612 in an open-label clinical safety study. Background: ND0612…Plasma p-tau181, neurofilament light chain and association with cognition in Parkinson’s disease
Objective: To investigate the association of plasma p-tau181 and NfL with cognitive performance and cognitive progression in PD patients. Background: Cognitive impairment (CI) is a…Focused ultrasound offers tremor relief in multiple system atrophy patients
Objective: To report on the efficacy and safety of MRI-guided focused ultrasound (FUS) VIM-thalamotomy in patients with multiple system atrophy (MSA). Background: FUS has established…A Phase 1b study to test the safety, pharmacokinetics, and pharmacodynamics of a novel inflammasome inhibitor in early-stage Parkinson’s disease: Rationale and study design
Objective: To describe the study design of a Phase 1b to test the safety, pharmacokinetics, and pharmacodynamics of a novel inflammasome inhibitor in individuals with…DUtch PARkinson Cohort (DUPARC): Contrast Sensitivity and Retinal Changes in Early Parkinson’s Disease Patients
Objective: To identify and characterize the correlation between static contrast sensitivity (SCS), dynamic contrast sensitivity (DCS), and thickness of the internal plexiform layer (IPL) in…To Prescribe or Not to Prescribe: Assessing the impact of Parkinson’s nurse prescribers
Objective: Within the UK, after successful completion of a formally recognised programme Parkinson’s Nurse Specialists (PNS) can act as independent prescribers, and as part of…Preliminary results on the cognitive profile in prodromal Parkinson’s disease – a prospective study
Objective: This study aims to investigate the cognitive profile in people with REM-sleep behavior disorder (RBD) and hyposmia, in a prodromal Parkinson’s disease (PD) cohort.…Magnetic Resonance Image-guided high-intensity focused ultrasound (MRIgFUS) subthalamotomy in Spanish Parkinson’s disease (PD) patients.
Objective: To describe our preliminary results of MRIgFUS subthalamotomy in two PD patients. Background: MRIgFUS thalamotomy has become the preferred surgical approach for refractory essential tremor…
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