Five for the price of one- A multidirectional micro-electrode recordings for DBS Surgery
Objective: To examine the use of a multidirectional micro electrode during Deep Brain Stimulation (DBS) surgery for Parkinson's Disease (PD) in 9 patients. Background: Micro-Electrode…Different longitudinal manifestations in dopaminergic dysfunction in REM sleep behavior disorder
Objective: To explore the different patterns of dopaminergic dysfunction between iRBD patients who convert to Parkinson’s disease (PD)/dementia with Lewy bodies (DLB) and those who…GLUT1 Deficiency Syndrome with Novel mutation responsive to GPi DBS
Objective: To describe a case of a patient with a progressive primary isolated generalized dystonia of childhood onset associated to a novel SLC2A1 mutation with…Retinal thickness as a marker of disease progression in progressive supranuclear palsy
Objective: We measured changes of retinal thickness, and compare them with clinical features and intracranial neurodegeneration in progressive supranuclear palsy (PSP) cohort. Background: PSP has a…Exosomes from human dental pulp stem cells as a cell-free drug delivery vehicle in vitro and in vivo chronic PD rat model through the intranasal route targeting efficacy & bio-distribution.
Objective: To evaluate the drug encasement in human dental pulp stem cell derived exosomes and its delivery in vitro in single cell level using fluorescence…Evaluation of α-synuclein pathology and function in dopaminergic neurons derived from LRRK2 I1371V PD patient iPSCs
Objective: To evaluate cellular pathogenesis in DA neuron function, and α-synuclein pathology using LRRK2-I1371V PD iPSC. Background: It is reported for complex-neurodegenerative disorders like PD,…Mutational effects of LRRK2 I1371V in astrocytes derived from patient specific iPSCs
Objective: To identify the LRRK2 I1371V mutational effects on astroglial biology involving glutamate metabolism and glutathione machinery. Background: The underlying cause of most of the familial…Can membrane association of α-synuclein aggregates lead to stress in the astrocytic endoplasmic reticulum?
Objective: To study the association extracellularly added wildtype-WT and A30P/A53T mutant α-synuclein aggregates with the astrocytic membrane and to evaluate the effect of these peptides…Psychotherapy as a potential treatment for neuropsychiatric startle syndromes of Latah – a case report
Objective: Our report aims to discuss psychotherapy as a treatment modality for Latah. Background: Latah is a culture-specific startle syndrome (classically identified in Malaysian/Indonesian patients)…Fundamental changes in Nerve Conduction Velocity and hyperpolarization latency of action potential of Sciatic nerve at the pre-motor phase in a chronic PD in vivo model: a neurotool for Parkinson’s disease diagnosis
Objective: To evaluate the changes in NCV and hyperpolarization latency of action potential of Sciatic nerve at the pre-motor phase in MPTP induced chronic PD…
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