Mutation screening and burden analysis of AOPEP in dystonia in a Chinese population
Objective: To explore the genetic involvement of AOPEPin dystonia in East Asian population. Background: Recently, AOPEPwas identified to be a novel likely causative gene of autosomal recessive dystonia.…Automated error detection when applying the protocol for the monitoring of motor function in patients with Parkinson’s disease using smartwatches.
Objective: To validate an automatic classification system for the identification of errors in the performance of standardized MDS-UPDRS III exercises by using inertial sensors from…Single-cell characterization of patient midbrain tissue reveals tissue remodeling and glial activation in Parkinson’s disease
Objective: We aim to characterize the contribution of each midbrain cell type to PD pathology, and to identify cell types associated with genetic PD-risk variants.…NONINVASIVE BRAINSTEM MODULATION FOR THE TREATMENT OF NONMOTOR SYMPTOMS IN PARKINSON’S DISEASE: A RANDOMIZED CONTROLLED TRIAL AND OPEN LABEL EXTENSION STUDY
Objective: A multi-site double-blinded pivotal randomized controlled trial (RCT) with an open label extension (OLE) study has been initiated to evaluate the safety and efficacy…Blood neurofilament light chain as a biomarker of Parkinson’s disease
Objective: The objective of the study was to analyse blood neurofilament light chain (NfL) levels in patients with Parkinson’s disease (PD) and healthy controls (HCs),…Feasibility of artificial intelligence in predicting early phenotype conversion of REM Sleep Behavior Disorder
Objective: The goal of this study was to investigate the feasibility of deep learning in the prediction of disease conversion in RBD patients. Background: Rapid…Sleep stability, arousals and cycle structure in alfa-synucleinopathies: a comparative study between isolated REM sleep behaviour disorder (iRBD), Parkinson’s Disease (PD) and Dementia with Lewy Bodies (DLB)
Objective: To compare sleep stability, arousals and sleep cycle structure between two sets of diagnosis: iRBD vs PD vs DLB; patients with RBD (RBD+) vs…It takes a village: An interdisciplinary care model for atypical Parkinsonism
Objective: To describe one interdisciplinary clinic designed to offer comprehensive care to patients with atypical parkinsonism syndromes, and to share the lessons learned which may…High- and Low-Frequency Deep Brain Stimulation in the Subthalamic Nucleus differentially modulate Response Inhibition and Action Selection in Parkinson’s Disease
Objective: The aim of this project was to investigate how high- and low-frequency deep brain stimulation (DBS) modulate impulsive actions in the antisaccade task as…Coexistence of Parkinson’s Disease and Myasthenia Gravis: Disease Characteristics and Confusion
Objective: In order to alert clinicians to the possibility of the coexistence of the two diseases and optimize the management of both conditions. Background: Parkinson’s…
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