Acute movement disorder with atypical topography. Acute hemichorea secondary to cortical stroke.
Objective: We present a case of acute hemichorea secondary to cortical infarction in the MCA territory. Background: Acute abnormal movements secondary to stroke occur in…High Intensity Interval Training for people with Parkinson’s disease: individual response patterns of (non-)motor symptoms and blood-based biomarkers – a crossover single-case experimental design
Objective: To quantify individual response patterns of motor symptoms to alternating exercise modalities, along non-motor functioning and blood biomarkers of neuroplasticity and neurodegeneration. Background: Physical…The effect of APOE ε4 on striatal vesicular monoamine transporter-2 density in Parkinson’s disease
Objective: To evaluate the effect of apolipoprotein E 4 (APOE 4) on striatal vesicular monoamine transporter-2 (VMAT2) density in Parkinson’s disease (PD).To evaluate the effect…Effect of ADX-88178, a highly-selective mGlu4 PAM, on parkinsonism, dyskinesia and psychosis-like behaviours in the MPTP-lesioned marmoset
Objective: To investigate the effect of the metabotropic glutamate 4 (mGlu4) positive allosteric modulator (PAM) ADX-88178 on parkinsonism, dyskinesia and psychosis-like behaviours (PLBs) in the…Combined approach in the diagnostic of Parkinson’s disease
Objective: Our aim was to develop and scientifically substantiate set of criteria for early(preclinical) diagnosis of neurodegenerative disorders with the assessment of a number of…Peroperative use of the MDS-UPDRS Motor Section: Agreement between Sitting and Supine position
Objective: To assess the level of agreement between the MDS-UPDRS-III in sitting and supine position. Background: The clinical effect during stereotactic neurosurgery for Parkinson’s disease…Non-intrusive Video-Based Solution for Continuous Quantitative Monitoring of Parkinson’s Patients’ Motor Functions
Objective: Feasibility and preliminary validation of a marker-less solution for automatic capture and quantification of movements during prespecified tasks of people with Parkinson’s (PwP) using…Differential effect of dopaminergic medication on smooth pursuit vs. saccadic eye movements Parkinson’s disease
Objective: To assess the effect of dopaminergic medication on eye movements in Parkinson’s disease (PD). Background: PD is the second most common neurodegenerative disease, characterised…Polyaromatic hydrocarbons in Ambient Particulate Matter (PM 2.5) mediate neurodegeneration through the olfactory-brain axis in C57BL/6 mice
Objective: To delineate the molecular mechanisms involved in bidirectional olfactory-brain-induced neurodegeneration caused by exposure to ambient particulate matter (PM2.5). Background: Air pollution has been linked…Development and Validation of an Algorithm to Automatically Assess Motor Symptoms of Parkinson’s Disease
Objective: To assist non-specialists in evaluating patients with advanced Parkinson's disease who have difficulty visiting specialists’ hospitals, we developed an algorithm to automatically rate the…
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