Nocturnal Polyuria in Parkinson’s Disease
Objective: To characterise the prevalence of nocturnal polyuria in a cohort of people with Parkinson’s disease (PD) with lower urinary tract symptoms. Background: Lower urinary…MRI to investigate cerebrovascular changes in Parkinson’s disease
Objective: To determine the value of MRI-derived cerebrovascular metrics and their relationship with global cognitive impairment in Parkinson’s disease (PD). Background: Cognitive impairment is a…Sex-specific factor analysis-derived profile of neuropsychiatric symptoms predicting dementia conversion in Parkinson’s disease
Objective: Neuropsychiatric symptoms (NPS) are closely associated with cognitive decline in patients with Parkinson’s disease (PD). We investigated which baseline profile of NPS predicts the…Remote identification of early, sensor-based markers of Parkinson’s Disease using participants’ smartphones: The Parkinson Progression Marker Initiative Digital sub-study
Objective: To summarize the design of the Parkinson’s Progression Markers Initiative (PPMI) Digital sub-study. The study objective is to identify the earliest signs and symptoms…What, when and how should the information on iRBD and risk of Parkinson’s disease and related conditions be communicated?
Objective: To investigate what, when and how patients with iRBD would like to receive information regarding the potential future implications of having iRBD, once diagnosis…Patterns of early-phase 18F-FP-CIT PET images and the risk of dementia conversion in Parkinson’s disease
Objective: This study aims to investigate the prognostic relevance of the patterns of early-phase 18F-fluorinated N-3-fluoropropyl-2-beta-carboxymethoxy-3-beta-(4-iodophenyl) nortropane (18F-FP-CIT) positron emission tomography (PET) images in patients…Central olfactory structure atrophy is linked to synucleinopathy conversion in idiopathic REM sleep behavior disorder
Objective: We hypothesized that early structural changes in the brain olfactory relevant structures may help early identification of those at risk of future disease conversion…Novel strategies based on sensory electrical stimulation to manage tremor in Parkinson’s disease. A pilot study.
Objective: Tremor can be a disabling motor symptom in patients with Parkinson´s disease (PD) and in some patients is refractory to medication. Here we present…Gait abnormalities relate to increased extracellular water in the substantia nigra in Parkinson’s disease patients
Objective: The aim of this study was to investigate the role of substantia nigra microstructural integrity in parkinsonian gait impairments. Background: Gait impairments are common…APEG-PCL Nanoparticles Containing Rifampicin Target Dopaminergic Neurons to reduce α-synuclein aggregation
Objective: There were accumulating evidence proving that rifampicin could protect neurons from apoptosis in Parkinson's disease in-vitro model by regulating SUMO modification of α-synuclein. However,…
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